In this study, human embryonic kidney (HEK)-293 cells stably expressing human, Drosophila, or a chimeric serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT, dSERT, and H(1-281)D(282-476)H(477-638), respectively) were used to explore the ability of two libraries of structurally distinct psychostimulants to inhibit 5-HT uptake. One library consisted of 3-phenyltropane analogs, whereas the s...

INTRODUCTION....................................................................... 43 ANAEROBIC MICROBIAL PROCESSES ....................................................................... 43 Microbial Diversity......... 0 43 Representative Degradative Pathways of Aromatic Compounds under Anaerobic Conditions ...............44 METABOLISM OF HOMOCYCLIC AROMATIC COMPOUNDS UNDER ANAEROBIC CONDITIO...

Salvia plants belong to the Lamiaceae family and are recognized as being strongly aromatic, widely used for different purposes in culinary or traditional medicine. These well rich phenolic acids, flavonoids terpenic compounds, which exhibit health-beneficial activities, protecting against oxidative inflammatory-related diseases, such diabetes obesity. Because of these properties, phytochemicals...

Aromatic rings form energetically favorable interactions with many polar groups in chemical and biological systems. Recent molecular studies have shown that sulfonamides can chelate metal ions hydrogen bonds, however, it is presently not established whether the sulfonamide functionality also interacts aromatic rings. Here, synthetic, spectroscopic, structural, quantum analyses on 2,6-diarylbenz...

Rhenium complex, [ReBr(CO)3(thf)]2-catalyzed reactions between aromatic imines and either acetylenes or α,β-unsaturated carbonyl compounds gave indene derivatives in good to excellent yields. These reactions proceed via C–H bond activation, insertion of acetylenes or α,β-unsaturated carbonyl compounds, intramolecular nucleophilic cyclization, and reductive elimination. Indene derivatives were a...

Atmospheric processing of aromatic compounds, which are known pollutants in urban air occurring predominantly from road transport sources, are a major contributor to photochemical oxidant formation as evidenced by the formation of ozone. It is believed that urban atmospheres contain a mixture of in excess of 100 speciated aromatic volatile organic compounds (VOC). Recent studies in understandin...

Aromatic bromides are important chemicals in nature and chemical industries. However, their traditional synthesis routes suffer from low atomic economy pollutant formation. Herein, we show that organic–inorganic hybrid perovskite methylammonium lead bromide (MAPbBr3) nanocrystals stabilized aqueous HBr solution can achieve simultaneous aromatic bromination hydrogen evolution using as the bromin...

Aim. Cancer continues to pose a serious threat human health. Euphorbia plants are rich in phenolics, aromatic esters, steroids and several bioactive compounds. Studies have shown the presence of large number compounds E. echinus including flavonoids, proanthocyanins. Method. There it was investigated cytotoxic effects methanolic extract on K562, HL60, Ishikawa, Raji SH-SY5Y cells. Results. The ...

The anaerobic metabolism of phthalate and other aromatic compounds by the denitrifying bacterium Pseudomonas sp. strain P136 was studied. Benzoate, cyclohex-1-ene-carboxylate, 2-hydroxycyclohexanecarboxylate, and pimelate were detected as predominant metabolic intermediates during the metabolism of three isomers of phthalate, m-hydroxybenzoate, p-hydroxybenzoate, and cyclohex-3-ene-carboxylate....