Electroconvulsive therapy (ECT) is one of the most effective treatments for major depressive disorder (MDD). Biomarkers predicting individuals’ response to ECT would provide more successful and personalized treatment strategies. This study aimed investigate whether dynamic functional connectivity (dFC) estimated from resting-state fMRI (rs-fMRI) predicts outcome.

A case of prolonged and refractory neuroleptic malignant syndrome was treated successfully with electroconvulsive therapy. Neuroleptic malignant syndrome and its treatment are reviewed.

Physicians who use electroconvulsive therapy (ECT) need to be vigilant for unstable medical conditions before and during the course of treatment. This brief review is intended to highlight some basic principles and specific concerns that may be encountered in the use of ECT in patients who have comorbid medical illness. For more extensive discussions, I refer the reader to recent reviews of ECT...

ajor depressive disorder is among the most prevalent psychiatric disorders and is a leading cause of morbidity and lost productivity. 1 The 1-year prevalence of major depressive disorder in the Canadian population is 3.2%–4.6%. 2 A large, multisite prospective trial showed that only 28% of patients ex-peri ence remission following monotherapy with a serotonin reuptake inhibitor. 3 Further, remi...

Electroconvulsive therapy (ECT) is the most effective treatment for severe major depressive episodes (MDE). Nonetheless, firmly established associations between ECT outcomes and biological variables are currently lacking. Polygenic risk scores (PRSs) carry clinical potential but with response in psychiatry seldom reported. Here, we examined whether PRSs disorder, schizophrenia, cross-disorder, ...

In 54 patients presenting for electroconvulsive therapy, the concentration of serum potassium was measured before and after the induced convulsion modified with a standard anaesthetic technique of methohexitone and suxamethonium. It was found that there was a statistically significant rise in serum potassium, but that the duration of convulsion had no significant effect on that rise in serum po...

Electroconvulsive treatment (ECT) for mental disorders is considered to be safe and effective when administered according to standard protocols for appropriate indications.1-4 It can produce transient cognitive impairment, but not structural damage, to the brain and is remarkably free from serious complications. Deaths after ECT are reported to occur at a rate of 2 per 100,000 treatments, about...

objective: the aim of this study was to identify prognosis factors associated with recurrence in patients ‎with bipolar disorder.‎‎ method: this retrospective cohort study was conducted in hamadan province, the west of iran. all ‎patients (n = 400) with bipolar disorder who were hospitalized for the second time or more ‎during april 2008 to september 2014 were included in this study. ordinal lo...

Atropine has been used in ECT to eliminate parasympathetically mediated dysrhythmias. However, it may increase heart rate and myocardial workload. The aim of this study was to investigate the effect of atropine premedication on the heart rate and blood pressure. Study was performed in 80 patients referred for a course of ECT. They enrolled randomly in one of the two equal groups to receive atro...