INTRODUCTION The purpose of this study was to analyse the value of 3-dimensional computed tomography cholangiography (3D-ERC) compared to conventional retrograde cholangiography in the preoperative diagnosis of hilar cholangiocarcinoma (HC) with special regard to the resection margin status (R0/R1). PATIENTS AND METHODS All hepatic resections performed between January 2011 and November 2013 i...

The apolipoprotein E (APOE) ε4 allele associates with accelerating the conversion from amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD), whereas the protectiveAPOEε2 allele appears to be against the disease. Moreover, entorhinal cortex (ERC) is one of the earliest brain regions of AD pathology that disrupts the formation of episodic memory. To investigate the effects of APO...

Ejectors have gained renewed interest in the last decades, especially heat-driven refrigeration systems, to reduce load of compressor. Their performance is usually influenced by many factors, including working fluid, operating conditions and basic geometrical parameters. Determining relationships between these factors accurately predicting ejector over a wide range remain challenging. The objec...

The growth of a large proportion of estrogen receptor-positive breast tumors is stimulated by estrogen and can often be controlled through antiestrogen therapy. Resistance to antiestrogen (AE) therapy can occur »huetumors retain the expression of estrogen receptors (ERc) and remain functionally responsive to estrogens. The ability of specific an tiestrogen binding sites (AEBS) to prevent AE fr...

Pancreatic ductal adenocarcinoma (PDA) is a highly lethal disease, which is usually diagnosed in an advanced stage. We have established transgenic rats carrying a mutated K-ras gene controlled by Cre/loxP activation. The animals develop PDA which is histopathologically similar to that in humans. Previously, we reported that serum levels of N-ERC/mesothelin were significantly higher in rats bear...