This paper studies structural properties of the optimal resource allocation policy for singlequeue systems. Jobs arrive at a service facility and are sent one by one to a pool of computing resources for parallel processing. The facility poses a constraint on the maximum expected sojourn time of a job. A central decision maker allocates the servers dynamically to the facility. We consider two mo...

Background—The antiplatelet effect of aspirin is attributed to platelet cyclooxygenase-1 inhibition. Controversy exists on the prevalence of platelet resistance to aspirin in patients with coronary artery disease and effects of aspirin dose on inhibition. Our primary aim was to determine the degree of platelet aspirin responsiveness in patients, as measured by commonly used methods, and to stud...

Teicoplanin, a new glycopeptide antibiotic, is structurally related to ristocetin, an antibiotic known to induce human platelet agglutination and, thus, thrombocytopenia and thromboembolic side effects. The aim of this study was to evaluate the effects of teicoplanin on platelet function in vitro and ex vivo and on blood coagulation ex vivo. In the in vitro studies, spontaneous platelet aggrega...

A visual programming facility is described which is based on a visual rule formalism. It permits programmers to specify the behaviors of agents in the class of program objects in the Agentsheets system of Repen-ning. The resulting agents can be used in designing simulations for two-dimensional cellular worlds such as in automobile traac ow situations, video games, and cellular automata studies....

A framework for computing consistent answers to boolean aggregate queries in numerical databases violating a given set of aggregate constraints is introduced. Both aggregate constraints and queries are aggregation expressions consisting of linear inequalities on aggregate-sum functions. In particular, our approach works for a specific but expressive form of aggregation expressions (called stead...

BACKGROUND The antiplatelet effect of aspirin is attributed to platelet cyclooxygenase-1 inhibition. Controversy exists on the prevalence of platelet resistance to aspirin in patients with coronary artery disease and effects of aspirin dose on inhibition. Our primary aim was to determine the degree of platelet aspirin responsiveness in patients, as measured by commonly used methods, and to stud...

The dihydropyridine calcium channel antagonists, such as nifedipine, inhibit platelet aggregation in vitro and ex vivo, but the mechanism by which this occurs is uncertain. Bay K 8644 (BAY) is a substituted dihydropyridine that has effects on voltage-dependent calcium channels in cardiac and smooth muscle that are opposite the effects of nifedipine. To evaluate the mechanism responsible for dih...