New macroscopic mechanical model of a two-phase composite based on the Lagrange function and principle least action was developed. The key advantage is direct consideration phase interaction defects (discontinuities) at interphase boundaries. As distinct from classical models, equations developed are solved in terms velocities elastic waves composite. effective (macroscopic) moduli calculated u...

Proper organization of microtubule polymers is crucial to the form and function of all eukaryotic cells. Whether growing, dividing or polarizing, different cell types—be they neurons, plant cells or fungal cells—organize specialized microtubule patterns appropriate for their needs. Is it possible to identify the set of factors sufficient to organize microtubules in a specific cell, and to under...

Background: A patient with multiple myeloma developed myelodysplastic syndrome (MDS). Chromosomal analysis performed after the development of MDS revealed monosomy of chromosome 9 in all the meta-phases. We wished to identify the extent of the clone with the chromosomal abnormality originating from MDS clone. Methods: A correlative interphase study by fluorescence in situ hybridization (FISH) w...

in this paper we investigate the effect of a random transverse field, distributed according to a trimodal distribution, on the phase diagram and magnetic properties of a two-dimensional lattice (square with z=4),  ferromagnetic ising system consisting of magnetic atoms with spin-1. this study is done using the effectivefield theory (eft) with correlations method. the equations are derived using...

INTRODUCTION The limitation of cytogenetic analysis is that the Ph chromosome cannot be detected in clumped metaphase or in interphase cells. Fluorescence in situ hybridization (FISH) is a highly sensitive molecular genetic technique, which enables to detect break point cluster region--Abelson (BCR-ABL) complex and minimal residual disease in all Ph positive CML patients not only in metaphase b...

We report here several experiences of interphase cytogenetics, using fluorescence in situ hybridization (FISH) technique, for the detection of chromosome aberrations. FISH, using alpha satellite specific probes of 18, X, Y chromosomes, was done in interphase nuclei from peripheral blood of patients with Edwards' syndrome, Klinefelter's syndrome and Turner's syndrome with healthy male and female...

ions As mentioned above, the state space of a model M together with the property φ to be checked, is generally too big to be checked exhaustively. In order to reduce the state space of the model M, abstractions have to be made. The verification approach requires over approximations of the original model Mv: if the abstract model Mabs is proven to be correct with respect to the (safety) property...