Through both gain- and loss-of-TTF-1 expression strategies, we show that TTF-1 positively regulates vascular endothelial growth factor (VEGF) and that the VEGF promoter element contains multiple TTF-1-responsive sequences. The major signaling receptor for VEGF, i.e VEGFR2, also appears to be under a direct and positive regulation of TTF-1. The TTF-1-dependent upregulation of VEGF was moderately...

We analyze the constraints placed on individual CP-violating phases in the minimal supersymmetric extension of the Standard Model (MSSM) by current experimental bounds on the electric dipole moments (EDMs) of the neutron, Thallium, and Mercury atoms. We identify the four CP-violating phases that are individually highly constrained by current EDM bounds, and we explore how these phases and corre...

Document management is an unavoidable task. Previous research evaluated the effect of building document management systems exploiting spatial memory. It was proven that spatial memory enhances retrieval tasks for systems dealing with a small number of data items. We investigate the effect of spatial cues with scalable systems. We present EDM (Enhanced Data Mountain), a scalable picture manageme...

For successful commercial adaptation of the l-EDM (micro electro-discharge machining) process, there is a need to increase the process efficiency by understanding the process mechanism. This paper presents a model of the plasma discharge phase of a single discharge l-EDM event in deionized water. The plasma discharge is modeled using global model approach in which the plasma is assumed to be sp...

Continuous electrical discharge machining (EDM) is characterized by random positions, uncertain energy, extremely short time, narrow tool-workpiece gaps, etc. Theoretical research into the mechanisms leading to thermal erosion of material and associated surface morphology has become urgent allow continued development application EDM technology. Firstly, multi-pulse theory geometric optimization...

PURPOSE To explore the subconcepts of the Wittmann-Price Theory of Emancipated Decision-Making (EDM); which is proposed as a new theoretical model for the nursing care of women to increase women's satisfaction with decision-making about healthcare issues. Infant feeding method was used as the clinical exemplar. DESIGN AND METHOD A descriptive correlational design was used to test the five ide...

Advanced Ceramics find wide range of industrial applications. Cutting of advanced ceramic (SiC) is very difficult using conventional machining methods due to its low fracture toughness. In the past few years, researchers have claimed successful machining of ceramic composites using EDM process. Furthermore, increasing trend, necessity of miniaturization, micro components in MEMS and semiconduct...

Ti6Al4V alloy is highly used in the automotive and aerospace industry due to its good machining characteristics. Micro EDM drilling is commonly used to drill micro hole on extremely hard material with very high depth to diameter ratio. In this study, the parameters of micro-electrical discharge machining (EDM) in drilling of Ti6Al4V alloy is optimized for higher machining accuracy with less hol...

As higher education diversifies its delivery modes, our ability to use the predictive and analytical power of educational data mining (EDM) to understand students’ learning experiences is a critical step forward. The adoption of EDM by higher education as an analytical and decision making tool is offering new opportunities to exploit the untapped data generated by various student information sy...

It is well known that current equilibrium-based models fall short as predictive descriptions of natural ecosystems, and particularly of fisheries systems that exhibit nonlinear dynamics. For example, model parameters assumed to be fixed constants may actually vary in time, models may fit well to existing data but lack out-of-sample predictive skill, and key driving variables may be misidentifie...