Bacterial lipopolysaccharide (LPS, endotoxin) is a ubiquitous component of dust and air pollution and is suspected to contribute after inhalation to an activation of eosinophils in bronchial tissues of asthmatic patients, provoking inflammatory and allergic processes. We were therefore interested in the interaction of eosinophil granulocytes with LPS and have examined the activation of and upta...

Eo si nop hil ca tio nic pro tein (ECP) is a he te ro ge neous mo le cu le ori gi na ti ng from ac ti va ted eo si nop hil gra nu lo cytes. Bio lo gi cal ac ti vi ty and the cel lu lar con te nt of ECP are de ter mi ned by ge ne tic and pos ttran sla tio nal fac to rs. Se ve ral sin gle nuc leo ti de po lymor phis ms (SNPs) in hu man ECP ge ne (RNASE3) ha ve been des cri bed so far. ECP is a me...

Despite the burgeoning literature, evidence on how right-wing populists frame and act energy climate issues is limited even more scarce for other types of populist parties. We address this gap by exploring policy discourses, positions actions six European parties from Austria, Czechia, Greece, Italy, Poland Spain belonging to different populism. argue that there substantial largely neglected va...

OBJECTIVE: Search of best management for esophageal cancer (EC) patients (ECP) (T1-4N0-2M0) was realized. METHODS: We analyzed data of 499 consecutive ECP (age=56.3±8.9 years; tumor size=6.3±3.4 cm) radically operated and monitored in 19752017 (m=365, f=134; esophagogastrectomies (EG) Garlock=280, EG Lewis=219, combined EG with resection of pancreas, liver, diaphragm, aorta, VCS, colon transver...

Acute graft-versus-host disease (GVHD) is a major cause of mortality after allogeneic hematopoietic stem cell transplantation. We performed a phase II study on patients with acute steroid-refractory GVHD grades II to IV given extracorporeal photochemotherapy (ECP) weekly and analyzed response and long-term survival. Complete resolution of GVHD was achieved in 82% of patients with cutaneous invo...

The reliability of sensors that are used to monitor insitu electrochemical corrosion potential (ECP) for water condition of boiling water reactors (BWR) under an irradiation field is quite important [1]. In these sensors, the ion conductivity of yttria stabilized zirconia (YSZ) is utilized to measure the ECP. Therefore, for the accurate estimate of ECP, effects of irradiation on YSZ have to be ...

Photobacterium damselae subsp. piscicida (Phdp) is the causative agent of fish photobacteriosis (pasteurellosis) in cultured cobia (Rachycentron canadum) in Taiwan. A component was purified from the extracellular products (ECP) of the bacterium strain 9205 by fast protein liquid chromatography (FPLC) and identified as a phospholipase. An N-terminal sequence of 10 amino acid residues, QDQPNLDPGK...

Asthma is a chronic inflammatory disease that persists even during adequate therapy and asymptomatic episodes. We questioned whether "silent" chronic allergen exposure can induce and maintain airway inflammation and whether this still occurs during regular treatment with inhaled steroids. Twenty-six patients with house dust mite allergy and mild asthma (dual responders) participated in a parall...

Evolutionary mechanisms of origins of new gene function have been a subject of long-standing debate. Here we report a convincing case in which positive Darwinian selection operated at the molecular level during the evolution of novel function by gene duplication. The genes for eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) in primates belong to the ribonuclease gene f...