Ricin is a potential bioweapon that could be used against civilian and military personnel. Aerosol exposure is the most likely route of contact to ricin toxin that will result in the most severe toxicity. Early recognition of ricin exposure is essential if specific antidotes are to be applied. Initial diagnosis will most likely be syndromic, i.e., fitting clinical and laboratory signs into a pa...

There are well-known sex differences in the epidemiology and etiopathology of alcohol dependence. Male gender is a crucial risk factor for the onset of alcohol addiction. A directly modifying role of testosterone in alcohol addiction-related behavior is well established. Sex hormones exert both permanent (organizational) and transient (activational) effects on the human brain. The sensitive per...

OBJECTIVE Preterm infants are exposed to multiple painful procedures in the neonatal intensive care unit (NICU) during a period of rapid brain development. Our aim was to examine relationships between procedural pain in the NICU and early brain development in very preterm infants. METHODS Infants born very preterm (N=86; 24-32 weeks gestational age) were followed prospectively from birth, and...

OBJECTIVE   To examine associations between exposure to potentially traumatic events (PTEs) and clinical patterns of symptoms and disorders in preschool children. METHOD   Two hundred and thirteen referred and non-referred children, ages 24 to 48 months (MN = 34.9, SD = 6.7 months) were studied. Lifetime exposure to PTEs (family violence and non-interpersonal events) and recent stressful life...

background and objective: adult lead poisoning commonly occurs due to workplace exposures. neuro- psychological symptoms such as insomnia are reported as the early symptoms of chronic lead intoxication. this study aimed to evaluate association between blood lead level (bll) of workers from lead-zinc factories and their sleep quality. materials and methods : a cross-sectional study was performed...

Inflammatory bowel disease (IBD) is known to affect millions of people worldwide and primarily caused due abnormal immune responses intestinal microbes. IBD categorized under two main types – ulcerative colitis Crohn’s disease. Although the cause still an unsolved puzzle, its development can be attributed presence various risk factors including antibiotic use. The system point genesis anything ...

Objective: Neuro-endocrine tumors (NET) resulting in syndromes of serotonin excess can lead to cardiac involvement, and substantial mortality morbidity. This article is aimed at reviewing the pathophysiology, diagnosis management carcinoid heart disease (CHD). Results: The pathophysiology CHD stems from chronic exposure circulating vasoactive compounds. Frequent clinical evaluations, monitoring...