Abstract Summary: Accumulating evidence supports the impact of gut microbiota on clinical efficacy cancer immunotherapies against extraintestinal tumors, but it has not yet been addressed whether local commensals could also dictate prognosis patients with cancer. In this issue Cancer Discovery, Tsay and colleagues demonstrate that lower airway may harbor oral turn IL17-mediated inflammatory pat...

Cirrhosis is the end stage of progressive liver fibrosis, resulted from chronic inflammation and injury. Early identification risk factors appropriate treatment for hepatic decompensation paramount positive health outcomes. In this review study, we revisited mechanisms associated with gut dysbiosis intestinal hyperpermeability in advanced disease, further discussed nutritional strategies manage...

Evolutionary approaches are powerful tools for understanding human disorders. The composition of vaginal microbiome is important for reproductive success and has not yet been characterized in the contexts of social structure and vaginal pathology in non-human primates (NHPs). We investigated vaginal size, vulvovaginal pathology and the presence of the main human subtypes of Lactobacillus spp./ ...

The authors and the journal wish to retract the 27 September 2012 article cited above. Based on information discovered after publication and reported to the journal in November 2013, this article was found to contain sections that were taken verbatim from other sources without giving proper reference to the source and without identifying the citation as a word-by-word citation from that source....