Molecular motors play important roles within a biological cell, performing functions such as intracellular transport and gene transcription. Recent experimental work suggests that there are many plausible biochemical mechanisms that molecules such as myosin-V could use to achieve motion. To account for the abundance of possible discrete-stochastic frameworks that can arise when modeling molecul...

A multiway arbiter may be constructed from an interconnected structure of inverting gates which is a generalisation of the bistable flip-flop. Features of the dynamic behaviour of such a ‘multi-flop’ are illustrated by analysis and simulation based on a very simple non-linear dynamic model of each gate. Limitations of such a component as an arbiter are explained.

We describe methods for computing mean and variance approximations to instantaneous and average rate estimates obtained from continuous-time penalized ML dynamic PET image reconstructions. The derivation is based on writing the likelihood for the list-mode data as the limiting case of the likelihood for binned sinogram data as the temporal bin width goes to zero. We show that approximations of ...

Dynamic mechanical analysis (DMA) and ultrasonic measurements were carried out to study the temperature and frequency dependences of viscoelastic properties of polyurea. Master curves of Young’s storage and loss moduli were developed from the DMA data. Relaxation spectra were subsequently calculated by means of two approximate models, and the apparent activation energy of molecular rearrangemen...

In this work, we show that by varying the experimental conditions, the driving amplitude, a dynamic force microscope allows DNA properties to be selectively imaged. The substrate on which the DNA is fixed is a silica surface grafted with silane molecules terminated with amine groups. Use of small oscillation amplitudes favors the attractive interaction between the tip and the sample, while the ...

Recently there has been much interest in the Property Indexing Problem ([1],[7],[8]), where one is interested to preprocess a text T of size n over alphabet Σ (which we assume is of constant size), and a set of intervals π over the text positions, such that give a query pattern P of size m we can report all of the occurrences of P in T which are completely contained within some interval from π....

In Markov models of sequential decision processes, one is often interested in showing that the value function is monotonic, convex, and/or supermodular in the state variables. These kinds of results can be used to develop a qualitative understanding of the model and characterize how the results will change with changes in model parameters. In this paper we present several fundamental results fo...

Fatigue precracked specimens of three titanium alloys (6Al-4V, ELI, and Timetal 5111) were dynamically loaded in a drop weight tower system while the dynamic fracture toughness was inferred using Coherent Gradient Sensing, crack opening displacement, or strain gage methods. A comparison of the initiation toughness of the three materials as a function of loading rate and specimen thickness is made.