Color centers in diamond nanocrystals are a new class of fluorescence markers that attract significant interest due to matchless brightness, photostability and biochemical inertness. Fluorescing diamond nanocrystals containing defects can be used as markers replacing conventional organic dye molecules, quantum dots or autofluorescent proteins. They can be applied for tracking and ultrahigh-reso...

ownload ll populations within an increasing array of solid tumors, labeled cancer stem cells (CSC) or tumoring cells (TIC), have the ability to differentiate, self-renew, and replicate the original tumor in vivo. To hese cells have been distinguished from the bulk-tumor population by the expression pattern of celle proteins (e.g., CD24, CD44, CD133) and cellular activities, such as the efflux o...

The effects of histamine and its receptor antagonists on mouse bone marrow cells (MBMC) and MC3T3-E1 cells were studied to elucidate the precise molecular mechanisms underlying histamine activities in the respective cell types. The studied parameters were osteoclast differentiation and expressions of receptor activator of nuclear factor kappaB ligand (RANKL), histamine receptors (HR), and osteo...

PURPOSE A mouse model of age-related macular degeneration (AMD) was used to investigate the anti-angiogenic and anti-inflammatory role of UPARANT in laser-induced choroidal neovascularization (CNV). METHODS Choroidal neovascularization was induced by laser photocoagulation, and UPARANT was intravitreally injected. Some experiments were also performed after either intravitreal injection of ant...

We show here the first example of a hydrogel formed from a symmetrically functionalised diketopyrrolopyrrole aromatic core. Gelation is triggered by change in pH. Not only does this gelator form aggregated, entangled structures at low pH, but it also forms worm-like micelles at high pH. The structures at high pH can be aligned using shear to provide conductive materials.

Prinzmetal et a!, used 24Na for this purpose (1), while others used al bumin 1311 (2). With more extensive experience, procedures improved over the years until, in 1958, Pritchard et al (3) reported an effective method for the external precordial detection and determination of cardiac output with albumin †̃@†̃I. During this time, a good correlation with dye dilution technique by means of arte...

Stimulated emission on three UV transitions in Cd(+) has been observed by transferring population from inner-shell d-electron states, populated by photoionization, to outer-shell p-electron states using the output from a narrow-frequency dye laser. The use of similar techniques in other elements could eventually result in a number of new lasers in the UV and VUV.

Multilayer dye aggregation at the dye/TiO2 interface of dye-sensitized solar cells is probed via first principles calculations, using p-methyl red azo dye as an example. Our calculations suggest that the multilayer dye aggregates at the TiO2 surface can be stabilized by π…π stacking and hydrogen bond interactions. Compared with previous two-dimensional monolayer dye/TiO2 model, the multilayer d...