نتایج جستجو برای: dx centers
تعداد نتایج: 117950 فیلتر نتایج به سال:
Oncotype DX is recommended for coverage in early stage breast cancer when used to guide adjuvant chemotherapy treatment decisions for women who are lymph node negative (strong recommendation). The following genetic tests of cancer tissue are recommended for coverage (strong recommendation): BRAF gene mutation testing for melanoma Epidermal growth factor receptor (EGFR) gene mutation testing...
Let u(t; x); t 2 R; be an adapted process parametrized by a variable x in some metric space X, (!; dx) a probability kernel on the product of the probability space and the Borel sets of X. We deal with the question whether the Stratonovich integral of u(:; x) with respect to a Wiener process on and the integral of u(t; :) with respect to the random measure (:; dx) can be interchanged. This ques...
Zona occludens (ZO) proteins are molecular scaffolds localized to cell junctions, which regulate epithelial integrity in mammals. Using newly generated null alleles, we demonstrate that polychaetoid (pyd), the unique Drosophila melanogaster ZO homologue, regulates accumulation of adherens junction-localized receptors, such as Notch, although it is dispensable for epithelial polarization. Pyd po...
Correspondence to: Dr. Peter C. Appelbaum Department of Pathology Hershey Medical Center P.0. Box 850 Hershey, PA 17033 Telephone no,: (717) 531-5113 Telefax no.: (717) 531-7953 E-mail: [email protected] AC CE PT ED Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Antimicrob. Agents Chemother. doi:10.1128/AAC.01517-06 AAC Accepts,...
We show that a new type of hydrogel can be prepared by covalently inter-linking binary blends of microgel (MG) particles and that the swelling ratio and modulus of the gels can be predicted from their composition. In previous work we established that physical gels of glycidyl methacrylate (GMA) functionalised poly(methyl methacrylate-co-methacrylic acidco-ethyleneglycol dimethacrylate) microgel...
We report new measurements of the differential and total branching ratios for inclusive B decay to D, D and D and the first measurement of the same quantities for inclusive B decay to D. Here B is the mixture of Bd and Bu from Υ(4S) decay. Furthermore, since more than one charm particle (or antiparticle) of the same kind can be produced in B decay, here “inclusive B branching ratio” is used to ...
The Notch receptor signaling pathway regulates cell differentiation during the development of multicellular organisms. A number of genes are known to be components of the pathway or regulators of the Notch signal. One candidate for a modifier of Notch function is the Drosophila Suppressor of deltex gene [Su(dx)]. We have isolated four new alleles of Su(dx) and mapped the gene between 22B4 and 2...
Purpose: To develop a new and fully validated ion-pair spectrophotometric method for the determination of duloxetine hydrochloride (DX). Methods: Ion-pair spectrophotometric method was employed for the determination of duloxetine hydrochloride (DX) in bulk and pharmaceutical formulations using acidic dye methyl orange (MO) as ion-pairing agent at pH 4 (phthalate buffer). The yellow ion-pair com...
Pneumadin (PNM) is a biologically active decapeptide, which has previously been found to enhanced rat adrenal growth; the mechanism is indirect and probably involves the stimulation of both arginine-vasopressin (AVP) and ACTH release. The effects of 2- and 6-day PNM administration on the atrophic adrenal cortices of rats treated for 8 and 12 days, respectively, with daily subcutaneous injection...
PURPOSE DX-8951f is a novel hexacyclic camptothecin-analogue topoisomerase I inhibitor with both in vitro antileukemic activity and myelosuppression as a dose-limiting toxicity in solid tumor Phase I studies. DX-8951f is active in a human acute myeloid leukemia (AML) severe combined immunodeficient mouse model. In a leukemia Phase I study, we investigated the toxicity profile and pharmacokineti...
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