The cause of osteochondritis dissecans is still disputed. Axhausen (1912) suggested that the lesion could be embolic in origin, but Fairbank (1933) and Smillie (1951) believed that trauma was more likely to be responsible. The occurrence of multiple joint lesions, with a hereditary tendency, was demonstrated by Bernstein (1925), by Wagoner and Cohn (1931), by Gardiner (1955), and by Pick (1955)...

In a general, ultrasound screening programme, 12 453 women were examined at 16 and 32 weeks of pregnancy. The screening detected all limb deformities in the population during the study period. The seeming prevalence of dwarfism in the population was 750 per million.

the past. Most of the patients who had received radiation therapy showed high values , thus indicating that conventional radiation therapy is incomplete in most cases. In patients who had received surgical treatment , relatively low values were observed; however, only one-third of them showed values below 5 mi2g/ml. Among these patients, those whose values were below 10 mteg/ml, showed no clini...

Grebe syndrome antenatally because of history of previous two siblings affected with the same disorder and by comparing BPD and length of limb bones. In the affected male fetus the BPD was on the 50th percentile, whereas all the other long bones measured were less than 5th percentile(5,6), thus indicating limb reduction anomaly in the fetus. The family history of 2 previously affected sibs was ...

Numerous monogenic causes of growth disorders have been identified. Inheritance of most disorders covered by this panel is autosomal recessive, but familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome is considered to have autosomal dominant inheritance. This panel covers, but is not limited to, genes and disorders covered by the subpanels. and therefore enables ef...

K yphomelic dysplasia has been described as a generalised skeletal dysplasia characterised by a disproportionate growth, bowing of long bones, mild facial dysmorphia, and normal intelligence, with radiologically flattened vertebrae, short ribs, and metaphyseal flaring. Twenty-one cases have been reported in the literature. However the diagnosis in several cases from the literature has been disp...

The population of cells is described by a density function u(x, t), t represents time and x the measure of the cell-size. Functions μ, b and ν represents the mortality, division and migration processes which take place within the population and φ is the initial state of the population density. We assume that the environment is unlimited and all possible nonlinear mechanisms are ignored. In this...