When an ulcer-bearing area of the duodenum is viewed sideways after an opaque meal there may be visible a wedge-shaped area in which the barium is absent, with a central dark spot or depression above representing the actual ulcer, undulations in its neighbourhood, a shaded margin, and an interval or notch below. These points will be seen in Plate I. It is a key to the interpretation of other ph...

Cysteamine administration to rats is followed by a high incidence of peptic ulceration. The aim of the present study was to investigate the effect of cysteamine on gastric and duodenal mucosal histamine and gastric mucosal histamine formation capacity. After a four hour fast, cysteamine in doses of 50, 100, 200, 300, 400, and 500 mg/kg bodyweight was injected subcutaneously to male Wistar rats;...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1327 toms in 90 percent of infected persons. The prevalence of H. pylori infection varies geographically and has been demonstrated to be as high as 52 percent in the United States. Factors associated with higher infection rates are increasing age, African-American or Hispanic race, lower levels of education, and birth in a developing country. The patho...

Incidence Studies of the incidence of peptic ulceration can be no more than a mass of dull statistics, or, on the other hand, can raise fascinating problems-which are largely unanswered. For example, there have been several studies showing that there is a higher frequency of duodenal ulcers in the North of this island as compared to the South; and again there is good evidence the incidence of n...

BACKGROUND AND AIMS Factors predisposing to endoscopic ulcer formation or healing with non-steroidal anti-inflammatory drugs (NSAIDs) have not been well defined. METHODS We used multivariate analysis of data from three large similar trials to identify factors associated with endoscopic lesions and healing. We compared the effectiveness of omeprazole 20 mg and 40 mg daily, misoprostol 200 micr...

Background and aims: Factors predisposing to endoscopic ulcer formation or healing with non-steroidal anti-inflammatory drugs (NSAIDs) have not been well defined. Methods: We used multivariate analysis of data from three large similar trials to identify factors associated with endoscopic lesions and healing. We compared the effectiveness of omeprazole 20 mg and 40 mg daily, misoprostol 200 μg f...