A thiamine deficient patient presented to the emergency department with an acute confusional state, becoming unconscious and hypotensive following the administration of 32 g of intravenous glucose over 4 hr. A dramatic clinical improvement in his cardiovascular and neurological status followed a single intra-venous dose of 250 mg of thiamine. Profound thiamine deficiency was confirmed on bioche...

Salicylate of soda omitted ; iron and arsenic given instead. llf/i January 1893.?He feels very drowsy. Heart's sounds irregular,?pulse rapid and weak. Temperature goes up every eveuing to 99?F. 13tli January 1893.? Yesterday he was made to fast, and then santonine given. He passed two round worms this morning. 22nd January 1893.?Disease changed to beriberi; drowsiness, swelling of the upper ext...

THE TERM primary myocardial disease refers to a variety of cardiac enlargement which is of unknown cause and frequently leads to cardiac dilatation, congestive heart failure, and finally to death. There are a number of synonyms. The disorder is also called idiopathic myocardial hypertrophy,' myocardiopathy, cardiac hypertrophy of unknown cause, and, especially in Great Britain, cardiomyopathy. ...

was a single case of true beriberi seen, whether inside the hospital or in the outpatients' department. Some cases showed ' dys-sebacia' and phrynoderma as a minor evidence of vitamin B or vitamin A deficiency, but more gross signs of avitaminosis such as cheilosis, glossitis, photophobia with corneal vascularization or pellagra were rare. A few cases, however, did have spongy gums and scattere...