My summer research project as an REU student at UC Davis has mainly been an effort to create and motivate methods to achieve high-throughput screening of biomolecules from the National Cancer Institute (NCI) as possible treatments for various types of cancer. The hope of my advisor, Dr. Xiang Dong Zhu, and the rest of his group is to offer a competitive label-free drug screening technique to th...

Even though natural products has an excellent record as a source for new drugs, the advent of ultrahigh-throughput screening and large-scale combinatorial synthetic methods, has caused a decline in the use of natural products research in the pharmaceutical industry. This is due to the efficiency in generating and screening a high number of synthetic combinatorial compounds; whereas traditional ...

The term high content screening (HCS) has become synonymous with imaging screen using automated microscopes and automated image analysis. The term was coined a little over 10 years ago, since then the technology evolved considerably and has established itself firmly in the drug discovery and development industry. Both the instruments and the software controlling the instruments and analyzing th...

OBJECTIVE This study provides a cost-benefit analysis of preemployment drug screening and evaluates the sensitivity of this analysis to variation in its underlying assumptions. DESIGN Cost-benefit analysis, based on a cohort analytic study previously reported. SETTING Employees of the US Postal Service in Boston, Mass. PARTICIPANTS Estimates of costs and benefit are based on a cohort of 2...

In July 2008, revisions to the Criminal Code of Canada were implemented that provided police with the tools and powers to enhance the enforcement of laws against drug-impaired driving. Police were given the authority to demand a suspected drug-impaired driver submit to a Standardized Field Sobriety Test (SFST) and a drug influence evaluation by a Drug Recognition Evaluator (DRE), and to provide...

Multi-class, Multi-residue Analysis of 59 Veterinary Drugs in Livestock Products for Screening and Quantification Using Liquid Chromatography-tandem Mass Spectrometry-LC-MS/MS,Livestock products,Multi-class analysis,Veterinary drug