Nowadays about 74% of drugs are taken orally and found not to be as effective required. To improve such characters transdermal drug delivery system was emerged. Drug through the skin attain a systemic effect is commonly known differs from traditional topical delivery. Transdermal systems (TDDS) dosage forms involves transport viable epidermal or dermal tissues for local therapeutic while very m...

Drug safety issues continue to occur even with drugs that are approved after the completion of clinical studies. Drug-induced liver injury (DILI) is a major obstacle drug development, because primary site metabolism, and injuries caused during this process severe. Conventional in vitro human models, such as 2-dimensional hepatic cell lines, lack vivo physiological relevance, animal studies have...

Drosophila is one of the oldest and most powerful genetic models and has led to novel insights into a variety of biological processes. Recently, Drosophila has emerged as a model system to study human diseases, including several important neurodegenerative diseases. Because of the genomic similarity between Drosophila and humans, Drosophila neurodegenerative disease models exhibit a variety of ...

Antibacterial drugs used in animal might result in deposition of residues in meat, milk and eggs. The presence of antimicrobial residues in animal-originated food is critical problem in many countries over the years. Because, drug residues might result in various health hazards, both actual incidence of reactions and potential hazards perceived by the public, the most countries assess residue o...

The tumult arising from revelations of serious safety risks associated with widely prescribed drugs, including rosiglitazone (Avandia, GlaxoSmithKline), rofecoxib (Vioxx, Merck), and celecoxib (Celebrex, Pfizer), has led to widespread recognition that improvement is needed in our national system of ensuring drug safety. Notwithstanding federal legislation in 2007 that strengthened the authority...

Patient safety has always been a primary focus in the development of new pharmaceutical products. The predominant method for statistical evaluation and interpretation of safety data collected in a clinical trial is the tabular display of descriptive statistics. There is a great opportunity to enhance evaluation of drug safety through the use of graphical displays, which can convey multiple piec...

To improve characters of transdermal drug delivery system TDDS was emerged. Transdermal system, advantages, disadvantages of formulation design and.In Vitro drug permeation, moisture absorption and WVTR studies were. Design, Formulation and Evaluation of Transdermal Drug Delivery System of Budesonide. This work and the related PDF file are licensed under a Creative Commons.The purpose of this r...