The purpose of this research was to develop a matrix-type transdermal therapeutic system containing drug Diclofenac acid, Pressure Sensitive Adhesive (PSA) like acrylic adhesive by the solvent evaporation technique. Different concentrations of Labrasol, oleic acid and triacetin were used to enhance the transdermal permeation of diclofenac acid. Polyethylene monolayer film as a backing membrane ...

Sildenafil citrate is one of the most effective agents for treatment of erectile dysfunction which acts by inhibiting the cGMP-specific phosphodiesterase type 5. Extensive research work is focused on flash release dosage forms and especially fast dissolving films are successful to attract pharma-industry due to ease of preparation and opportunity to extend patent life. Films are widely acceptab...

Nanoparticles (NPs) show great promises in biomedical applications as the respiratory drug carrier system. Once reaching the alveolar region, NPs first interact with the pulmonary surfactant (PS) film, which serves as the first biological barrier and plays an important role in maintaining the normal respiratory mechanics. Therefore, understanding the interactions between NPs and PS can help pro...

Deparment of Pharmaceutics. Dean, Galgotias University,School of Medical and Allied Sciences, Deparment of Pharmaceutics. HOD, Galgotias University,School of Medical and Allied Sciences, Deparment of Pharmaceutics. [email protected] Contact no: 9718369167 ABSTRACT The oral route is more suitable than other route of administration of therapeutic agents due to low cost of therapy and eas...

The aim of this study was to formulate and characterize fast dissolving films containing dextromethorphan hydrobromide (DM) for oral use. Hydroxylpropyl methylcellulose E15 (HPMC) was used as the film forming polymer and crosspovidone (CPV), microcrystalline cellulose (MCC) were used as superdisintegrants. In this study, medicated films were prepared by solvent casting method. The physicochemic...