نتایج جستجو برای: drug combinations

تعداد نتایج: 659226  

خلیلی, غلامرضا, ساجدی, پروین, یوسف زادگان, صدیقه,

Background: Control of intracranial pressure (ICP) before, during and after neurosurgical operations is crucially important. Therefore, trying different methods and drug combinations to attain this goal is an ongoing effort in anesthesiology. In this study we compared two combinations of a narcotic agent with propofol in neurosurgical operations to control intracranial pressure.Methods: In this...

Journal: :The Journal of infectious diseases 2012
Patrick P J Phillips Stephen H Gillespie Martin Boeree Norbert Heinrich Rob Aarnoutse Tim McHugh Michel Pletschette Christian Lienhardt Richard Hafner Charles Mgone Alimuddin Zumla Andrew J Nunn Michael Hoelscher

A growing number of new drugs for the treatment of tuberculosis are in clinical development. Confirmatory phase 3 trials are expensive and time-consuming and the question of whether one particular drug combination can be used to treat tuberculosis is less important from a public health perspective than the question of which are the shortest, simplest, most effective, and safest regimens. While ...

Journal: :Molecules 2017
Hongjie Gao Zuojing Yin Zhiwei Cao Le Zhang

The growth and survival of cancer cells are greatly related to their surrounding microenvironment. To understand the regulation under the impact of anti-cancer drugs and their synergistic effects, we have developed a multiscale agent-based model that can investigate the synergistic effects of drug combinations with three innovations. First, it explores the synergistic effects of drug combinatio...

Journal: :Arthritis Research & Therapy 2009
Johannes WG Jacobs Johannes WJ Bijlsma

In a paper by Zimmermann and colleagues in this issue of Arthritis Research & Therapy, results of extended laboratory research with the drug combination of prednisolone and dipyridamole are reported. There seems to be a boost and extension of the glucocorticoid effect by the combination, without a clear increase of adverse effects, potentially allowing the application of lower dosages. However,...

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