In his Pulitzer Prize winning novel “The Emperor of all Maladies”, Dr. Siddhartha Mukherjee eloquently summarizes the history of rational drug design and its origins in understanding the impact of a foodderived bioactive compound (i.e., folic acid) in disease pathophysiology. Dr. Mukherjee reminds us that Sidney Farber’s 1948 seminal paper[1] in the New England Journal of Medicine set the frame...

non-medical use of prescription drugs (also known as medication diversion) is a common problem in middle and low income countries where monitoring capacities and law enforcement mechanisms are not efficiently developed (1-3). prescribed central nervous system (cns) stimulants, sedative hypnotics and long-lasting opioids are the most important drugs diverted throughout the world (1-4). non-medic...

The Sars-CoV-2 virus epidemic and the related threats have prompted considerations on criminal liability of a person who does not comply with restrictions, in particular order to cover mouth nose public spaces. Bearing mind special importance law petty offenses terms protection health, as well peace places. article deals issue enforcing places conducting proceedings this matter cases offences w...

Analyses of drugs of abuse are important for the prediction of and protection from the risk to human health, especially for young people. The use of drugs of abuse is increasing world wide and causing serious social problems. In Japan, abuse of methamphetamine (MP) is the most common and arrests for stimulant drug-related offences totaled 14624 in 2003. Recently, the use of 4,5-methylenedioxyme...

BACKGROUND There is an increasing probability that the psychiatrist will, willingly or not, come into contact with mentally ill offenders in the course of their practice. There are increasing rates of violence, substance abuse and other psychiatric disorders that are of legal importance. Therefore, the aim of this work was to investigate the rates of different mental disorders in 100 court repo...