In Drosophila, Insulin-like peptide 2 (Dilp-2) is expressed by insulin-producing cells in the brain, and is secreted into the hemolymph to activate insulin signaling systemically. Within the brain, however, a more local activation of insulin signaling may be required to couple behavioral and physiological traits to nutritional inputs. We show that a small subset of neurons in the larval brain h...

Fatal car crashes are the leading cause of death among teenagers in USA. The Graduated Driver Licensing (GDL) programme is one effective policy for reducing number teen fatal crashes. Our study focuses on Michigan during 1990–2004 excluding 1997, when GDL started. We use Poisson regression with spatially dependent random effects to model county level crash counts. develop a measurement error ac...

This paper describes the Kodak Imageliok TM OCR alphanumeric handprint module. There are two neural network algorithms at its cme: the first network is trained to find individual characters in an alphamuneric field, while the second one perfmns the classification. Both networks were trained on Gabor projections of the ociginal pixel images, which resulted in higher recognition rates and greater...

In recent years, Oman has seen a shift in the burden of diseases towards road accidents. The main objective of this paper, therefore, is to describe key characteristics of heavy vehicle crashes in Oman and identify the key driving behaviours that influence fatality risks. Crash data from January 2009 to December 2011 were examined and it was found that, of the 22,543 traffic accidents that occu...

OBJECTIVE This study examined recent trends in gender differences in the percentage of persons with driver's licenses as a function of age by comparing data from 2010 and 1995. METHOD The analysis used data from the Federal Highway Administration and the U.S. Census Bureau. RESULTS There are 2 main findings. First, the percentage of males with a driver's license decreased from 1995 to 2010 ...

The precise duplication of chromosomal DNA during each cell cycle is essential for the maintenance of genetic stability. Failure to correctly regulate chromosomal DNA replication could lead to losses or duplication of chromosome segments. The precise duplication of chromosomes is normally achieved by correct regulation of the replication licensing system. Here we review our current knowledge of...

In eukaryotes the entire genome is replicated precisely once during each S phase of the cell cycle. Cell-free extracts of Xenopus eggs support chromosomal DNA replication in vitro, apparently under the same cell cycle controls that exist in vivo.1,2 When DNA is added to the cell-free system it is assembled into chromatin, and then into structures resembling normal interphase nuclei,3 processes ...

oo many organizations view electronic records management (ERM) software selection through a narrow lens. Some enterprises will create massive spreadsheet-based matrices with lists of features and functions broken down in minute detail. These features and functions are weighted by priority, then added and scored to rank vendors and products based on empirical data. This can be a useful exercise ...

The advice given to upper limb amputees in the United Kingdom with regard to the use of driving appliances has often been somewhat variable. At best a full rehabilitation package has been provided, including the fitting of the appliances to the person's vehicle and contact with the driver's instructor, to the other extreme of issuing driving appliances to patients with no instruction at all. Th...

Novice young drivers suffer from increased crash risk that translates into over-representation in road injuries. In order to effectively confront this problem, a better understanding of the driving behavior of novice young drivers and of its determinants is needed. This study analyzes the behavior of novice young drivers within a Graduated Driver Licensing (GDL) program. Data on driving behavio...