Successive alternative cell fate choices in the imaginal disc epithelium lead to the differentiation of a relatively invariant pattern of multicellular adult sensory organs in Drosophila. We show here that the activity of Suppressor of Hairless is required for both the sensory organ precursor (SOP) versus epidermal cell fate decision, and for the trichogen (shaft) versus tormogen (socket) cell ...

Abstract. Widodo A, Lamid M, Effendi MH, Khailrullah AR, Kurniawan SC, Silaen OSM, Riwu KHP, Yustinasari LR, Afnani DA, Dameanti FNAEP, Ramandinianto SC. 2022. Antimicrobial resistance characteristics of multidrug and extended spectrum beta-lactamase producing Escherichia coli from several dairy farms in Probolinggo, Indonesia. Biodiversitas 23: 215-221. bacteria initially reside the digestive ...

in view of potential biological activities of small molecule polyamides, we synthesized some novel n-(2-aminoethyl)-1-benzyl-2- (alkylthio)-1h-imidazole-5-carboxamide (7a,b), and n-(2-(1-benzyl-2-(alkylthio) -1h-imidazole- 5-carboxamido) ethyl)-1-benzyl-2- (alkylthio)-1h-imidazole-5-carboxamides (8a,b) as antitumor agents. the antitumor activity of compounds 7a,b and 8a,b was studied at concent...

BACKGROUND CONTEXT Plasma-mediated radiofrequency-based ablation (coblation) is an electrosurgical technique currently used for tissue removal in a wide range of surgical applications, including lumbar microdiscectomy. In vitro and in vivo studies have shown the technique to alter the expression of inflammatory cytokines in the disc, increasing the levels of interleukin-8 (IL-8), which may prom...

Motivated by possible applications to condensed matter systems, in this paper we construct U(N) noncommutative Chern-Simons (NCCS) action for a disc and for a double-layer geometry, respectively. In both cases, gauge invariance severely constrains the form of the NCCS action. In the first case, it is necessary to introduce a group-valued boson field with a non-local chiral boundary action, whos...

traumatic retrolisthesis is a rare injury and may result in intervertebral disc extrusion and nerve root injury. these injuries are highly unstable and require surgery for decompression and stabilization. traumatic retrolisthesis of l5 with acute l5/s1 disc extrusion associated with nerve root injury has not been reported previously in english literatures. we herein report a case of traumatic r...

Context. Thanks to ongoing efforts compute accurate stellar ages, we are able characterise stars in different regions of the Milky Way. The Gaia and Kepler space-missions, along with ground-based spectroscopic surveys such as APOGEE, provide a unique way study chemo-kinematics relations function age through Galactic populations new constraints evolution models. Aims. We investigate properties d...

ABSTRACT Recent observations of supermassive black holes have brought us new information on their magnetospheres. In this study, we attempt a theoretical modelling the coupling with jets and discs, via three innovations. First, propose semi-analytical MHD description steady relativistic inflow–outflow structure characteristic to extraction hole rotational energy. The mass-loading is ensured in ...

Although degeneration of the intervertebral disk has historically been described as a misbalance between anabolic and catabolic factors, the role of inflammatory mediators has long been neglected. However, past research clearly indicates that inflammatory mediators such as interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor-α are expressed at higher levels in "diseased" intervertebral dis...

Caspase-2 was reported to be involved in a number of apoptotic pathways triggered by various stimuli. However, the molecular mechanism of procaspase-2 activation in the course of apoptosis remains poorly defined. In this report, we demonstrate that procaspase-2 is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex (DISC) in human T- and B-cell lines. We show that procaspase-2 is...