نتایج جستجو برای: dotatate

تعداد نتایج: 876  

Journal: :Biomedical Journal of Scientific & Technical Research 2018

2016
Antonio Balestrieri Elena Magnani Fiorella Nuzzo

A 75-year-old man was hospitalized because of severe hypokalaemia due to ACTH dependent Cushing's syndrome. Total body computed tomography (TBCT) and 68 Gallium DOTATATE PET/CT localized a voluminous prostate tumour. A subsequent transurethral prostate biopsy documented a small cell carcinoma positive for ACTH and calcitonin and negative for prostatic specific antigen (PSA) at immunocytochemica...

Journal: :Journal for ImmunoTherapy of Cancer 2021

Background The use of CAR T cells for solid tumors has a number challenges, such as lack tumor-specific targets, cell exhaustion, and the immunosuppressive tumor microenvironment. To address these AffyImmune developed technologies to affinity tune track in patients. targeting moiety is tuned preferentially bind overexpressing target while leaving normal with low basal levels untouched, thereby ...

Journal: :Diagnostics 2013
Yin Wu Andreas Klaus Pfeifer Rebecca Myschetzky Rajendra Singh Garbyal Palle Rasmussen Ulrich Knigge Michael Bzorek Michael Holmsgaard Kristensen Andreas Kjaer

Peptide receptor radionuclide therapy (PRRT) is a relatively new mode of internally targeted radiotherapy currently in clinical trials. In PRRT, ionizing radioisotopes conjugated to somatostatin analogues are targeted to neuroendocrine tumors (NETs) via somatostatin receptors. Despite promising clinical results, very little is known about the mechanism of tumor control. By using NCI-H727 cells ...

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