This study evaluated the efficacy of computed tomography (CT)-based three-dimensional (3D) dose-volume parameters of the rectum as predictor for late rectal complication (LRC) in cervical cancer patients treated with radiotherapy alone. Eighty-four patients treated with a combination of external radiotherapy and high-dose-rate intracavitary brachytherapy between January 2000 and December 2004 w...

Intensity-modulated radiation therapy (IMRT) is able to achieve good target conformance with a limited dose to organs at risk (OARs); however, IMRT increases the irradiation volume and monitor units (MUs) required. The present study aimed to evaluate the use of an IMRT plan with fewer segments and MUs, while maintaining quality in the treatment of nasopharyngeal carcinoma. In the present study,...

Background: Internal mammary lymph nodes (IMNs) are a potential site of metastasis for breast cancer. Targeting IMNs as part comprehensive regional nodal irradiation comes at the cost higher unwanted doses to critical nearby organs risk. Thus, efficacy and safety different radiotherapy techniques coverage this area remain elusive. Objectives: We present dosimetric comparison between partially w...

BACKGROUND Cure rate of early Hodgkin Lymphoma are high and avoidance of late toxicities is of paramount importance. This comparative study aims to assess the normal tissue sparing capability of intensity-modulated radiation therapy (IMRT) versus standard three-dimensional conformal radiotherapy (3D-CRT) in terms of dose-volume parameters and normal tissue complication probability (NTCP) for di...

Total body irradiation (TBI) is a well-established component of several conditioning regimens required before bone marrow or hematopoietic stem cell transplantation. In this work, we validate the imparted dose in TBI technique using VMAT Médica Sur. We used an anthropomorphic phantom ATOM 702-D, CIRS (Norfolk, Virginia), add upper extremities homemade material and scanned it CT scanner GE 580RT...

PURPOSE To improve dose conformity and normal tissue sparing in patients with concave-shaped head and neck cancers by using tomotherapy and static step-and-shoot intensity-modulated radiation therapy (IMRT) and by comparing results with those of three-dimensional (3D) conformal radiation therapy (CRT) and two-dimensional (2D) radiation therapy. MATERIALS AND METHODS Treatment planning in 10 p...

BACKGROUND To compare the dosimetric differences among fixed field intensity-modulated radiation therapy (IMRT), single-arc volumetric-modulated arc therapy (SA-VMAT) and double-arc volumetric-modulated arc therapy (DA-VMAT) plans in rectal cancer. METHOD Fifteen patients with rectal cancer previously treated with IMRT in our institution were selected for this study. For each patient, three p...

ID: 4975 Title: Modeling Dose Delivery Accuracy of IMRT Head-and-Neck Cancer Treatment Purpose: To evaluate the impact of internal organ variations on IMRT treatments of head-and-neck cancers using different daily alignment techniques. Method and Materials: Eleven head-and-neck cancer patients were imaged twice weekly during their course of treatment (141 CT scans total) using an integrated CT-...

The purpose of this study is to evaluate the intensity modulated radiotherapy (IMRT) with the fixed collimator jaws technique (FJT) for the left breast and regional lymph node. The targeted breast tissue and the lymph nodes, and the normal tissues were contoured for 16 left-sided breast cancer patients previously treated with radiotherapy after lumpectomy. For each patient, treatment plans usin...