نتایج جستجو برای: dose assessment

تعداد نتایج: 855947  

Journal: :The New England journal of medicine 2011
G Michael Felker Kerry L Lee David A Bull Margaret M Redfield Lynne W Stevenson Steven R Goldsmith Martin M LeWinter Anita Deswal Jean L Rouleau Elizabeth O Ofili Kevin J Anstrom Adrian F Hernandez Steven E McNulty Eric J Velazquez Abdallah G Kfoury Horng H Chen Michael M Givertz Marc J Semigran Bradley A Bart Alice M Mascette Eugene Braunwald Christopher M O'Connor

BACKGROUND Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, but there are few prospective data to guide their use. METHODS In a prospective, double-blind, randomized trial, we assigned 308 patients with acute decompensated heart failure to receive furosemide administered intravenously by means of either a bolus every 12 hours or continu...

Introduction: Nuclear moisture density gauges are widely used in construction industry in different countries across the world, including Ghana, on a large scale. Like all irradiating devices, the nuclear gauges should be subjected to radiation safety assessment based on radiation protection and safety principles. Regarding this, the objective of this research was to i...

Journal: :Environmental Health Perspectives 1994
J M Samet W E Pepelko B Sonawane G E Hatch K E Driscoll G Oberdörster

The assessment of risks to human health associated with exposure to oxidant air pollutants has not received adequate attention despite the recognized public health threat posed by the ubiquitous presence of these compounds in the environment. In this article, research needs and uncertainties at each of the steps in the risk assessment of oxidant air pollutants are identified: hazard identificat...

Journal: :Environmental pollution 2008
R Matyssek H Sandermann G Wieser F Booker S Cieslik R Musselman D Ernst

Upcoming decades will experience increasing atmospheric CO2 and likely enhanced O3 exposure which represents a risk for the carbon sink strength of forests, so that the need for cause-effect related O3 risk assessment increases. Although assessment will gain in reliability on an O3 uptake basis, risk is co-determined by the effective dose, i.e. the plant's sensitivity per O3 uptake. Recent prog...

2011
E. Sarapultseva J. Malina A. Gorski

The effects of low-dose -irradiation on the crustacean Daphnia magna have been analyzed. Given that the LD50 for this species is approximately 100Gy, one-day-old daphnids were exposed to 10, 100 and 1000mGy of acute -rays. The survival of irradiated animals was evaluated over the maximum lifespan of 90 days. Increased mortality among irradiated at doses of 100 and 1000mGy daphnids was found. Ou...

Journal: :Regulatory toxicology and pharmacology : RTP 1995
I F Purchase T R Auton

It is common practice to base carcinogenic risk assessment on the view that there is no threshold for chemical carcinogenesis. In this context, the threshold is defined as a dose below which no effects are observed. Analysis of epidemiological and experimental data on chemical carcinogenesis confirms that no thresholds have been demonstrated in human or animal studies, including the ED01 study ...

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