The ability to recover sufficient amounts of deoxyribonucleic acid (DNA) from various biological evidentiary samples for individualization purposes is discussed. The chemistry and stability of DNA under various conditions is reviewed. The recovery of nondegraded DNA bears directly on the ability to successfully analyze such samples by restriction fragment length polymorphism analysis, as well a...

background: factor xiii deficiency (fxiiid) is an inherited rare bleeding disorder with some life threatening clinical manifestation including intracranial haemorrhage (ich). among all polymorphisms found in fxiiid, thrombin activatable fibrinolysis inhibitor (tafi) thr325ile gene polymorphism increases probability ofichabout 20 fold in patients with fxiii .so, in this study we aimed to evaluat...

meriones crassus, meriones persicus, and meriones libycus from different areas of khorasan provinces and yazd province were studied by use of random amplified dna polymorphism (rapd) technique. dna samples were analyzed by use of nine primers. genetic distance among samples varied between 0.24 and 0.78. dendrogram designed on the base of genetic distance shows separation of these species. in th...

The aim of our study was to see the effects of GSTP1 polymorphism on biomarkers of ageing, including micronuclei (MN), comet tail length, and relative telomere length in automobile repair workers, who are exposed to a broad spectrum of potential mutagens. The analysis was performed on buccal cells collected from occupationally exposed and non-exposed (control) subjects. Samples were analysed us...

Variations in DNA sequence generate polymorphisms which can be followed through families. A cloned gene specific probe for human complement 3 (C3) was hybridised to DNA samples digested with restriction endonucleases. The C3 probe detects several restriction fragment length polymorphisms (RFLPs) that occur frequently in the general population. These DNA alleles can be readily used in linkage an...

Increased expression of epithelial cell-derived neutrophil-activating peptide (ENA-78) has been reported in several immune and inflammatory conditions suggesting its role in inflammatory response. We have identified two single nucleotide polymorphisms in the promoter and exon 2 of the ENA-78 gene by scanning the full length gene using DHPLC DNA fragment analysis and DNA sequencing. The polymorp...