Phytoplankton inhabiting oligotrophic ocean gyres actively reduce their phosphorus demand by replacing polar membrane phospholipids with those lacking phosphorus. Although the synthesis of nonphosphorus lipids is well documented in some heterotrophic bacterial lineages, phosphorus-free lipid synthesis in oligotrophic marine chemoheterotrophs has not been directly demonstrated, implying they are...

Antisense oligonucleotides, complementary to certain gene sequences, are designed to hybridize to mRNA and inhibit the synthesis of disease related cellular or viral proteins (1-3). Although numerous in vitro studies have established a great deal of therapeutic potential for these oligonucleotides, there are still many unresolved properties of these oligomers which are critical to drug developm...

DNA dodecamers of the alternating d(CG).d(CG) sequence with six phosphate groups either charge-neutralized or substituted by neutral methylphosphonates across the major or minor groove have been subjected to energy minimization to determine the conformational effect of the asymmetric elimination of phosphate charge. We report bending angles, directions of bending, and detailed structural charac...

this paper investigates hollow and porous alumina nanospheres that were previously synthesized to be used for the dehydration of methanol to dimethyl ether (dme). as hollow nanostructures possess characteristics such as low density and high surface to volume ratio, their catalytic activity between hollow and porous structure is compared. for this purpose, three most important parameters (acidit...

Copper (II) complexes of three phosphonate ligands were prepared and fully characterized by elemental analysis, spectral and thermal studies. The IR spectral data showed that the phosphonate compounds behave as bidentate ligands coordinating to the copper ion through the P=O and NH groups. The electronic spectroscopic data support a distorted octahedral geometry around copper ion. The activity ...

The wild-type strain of Pseudomonas fluorescens was found to utilize a range of structurally diverse organophosphonates as its sole carbon or nitrogen sources. Representative compounds included aminoalkylphosphonates, hydroxyalkylphosphonates, oxoalkylphosphonates, and phosphono dipeptides. Among them, amino(phenyl)methylphosphonate,2-aminoethylphosphonate, aminomethylphosphonate, diisopropyl 9...