Introduction Diabetes is a major chronic disease that can lead to serious health problems and high healthcare costs without appropriate disease management and treatment. In the United States, the number of people diagnosed with diabetes and the cost for diabetes treatment has dramatically increased over time. To improve patients' self-management skills and clinical outcomes, diabetes management...

We present new VLA radio observations of a sample of dMe stars in X, U, K, and Q bands (from 8.4 to 43 GHz) obtained during an observing campaign in 1996 April-June. The aim of the project was to determine the spectral energy distributions of late-type dwarf flare stars to investigate the possible existence of an inversion of the spectrum slope at frequencies higher than 8 GHz. We also tried to...

The purpose of this study is to identify the risk factors for a recurrence or persistence of diabetic macular oedema (DME) after a sub-Tenon's capsule triamcinolone acetonide (STTA) injection. The medical records of 124 patients (124 eyes) treated by STTA were reviewed. The age, sex, HbA1c level, best-corrected visual acuity, central macular thickness, insulin use, pioglitazone use, systemic hy...

In a retrospective cross-sectional study, we too evaluated the systemic risk factors associated with sub-retinal fluid (SRF) pattern of DME. We compared 37 eyes with SRF pattern of DME (designated cases) versus 30 eyes having DME (sponge like retinal swelling or cystoid macular edema) without SRF (designated controls) on spectral domain-OCT. We too found that the SRF pattern was more common in ...

The US Federal Aviation Administration (FAA) is developing alternative navigation concepts to maintain operational capacity and efficiency even in the presence of a degradation of the Global Positioning System (GPS). One concept being studied for this alternate position navigation and timing (APNT) is a ground based passive ranging system. Such a system can achieve many benefits. It has few cap...

Activities of drug-metabolizing enzymes (DMEs) are known to change throughout the course of physical and sexual maturation, with the greatest variability noted during infancy and adolescence. The mechanisms responsible for developmental regulation of DME are currently unknown. However, the hormonal changes associated with puberty/adolescence provide a theoretical framework for understanding the...

We report the use of silicon chips with 16 DNA-modified electrodes (DME chips) utilizing DNA-mediated charge transport for multiplexed detection of DNA and DNA-binding protein targets. Four DNA sequences were simultaneously distinguished on a single DME chip with 4-fold redundancy, including one incorporating a single base mismatch. These chips also enabled investigation of the sequence-specifi...

Polyethylene glycol (PEG) is a non-ionic water soluble polymer that is used as an additive in protein solutions to induce protein crystallization. PEG in dilute solution concentrations and within a molecular weight range, induces an attractive protein-protein interaction. However the strength of this attractive proteinprotein interaction weakens with increasing PEG concentration and molecular w...

Diabetic retinopathy (more specifically diabetic macular edema, DME) is the most common cause of loss of vision in the working population in developed countries. Anti-vascular endothelial growth factor (anti-VEGF) agents considerably changed the treatment algorithms and improved prognosis of center-involving DME. Ranibizumab was the first approved anti-VEGF agent that revolutionized DME treatme...

Diabetic macular edema (DME) is a significant cause of blindness in the working population and is currently challenging to treat. Current interventions include focal laser or intravitreal injections. This article outlines a new treatment protocol based on the theory that peripheral ischemia is the precursor to angiogenesis, which will ultimately gather its momentum at the fovea. Extreme periphe...