Fulminant herpes hepatitis with disseminated extrahepatic involvement in pregnancy is rare and carries a high mortality risk. Although acyclovir remains standard first-line therapy, effective management of acyclovir-resistant disseminated herpes simplex virus (HSV) in pregnancy remains elusive. We present a case of disseminated HSV resistant to both acyclovir and foscarnet, the first double-age...

Coccidioidomycosis (CM) is an infection caused by the coccidioides fungus. The spectrum of the disease ranges from a mild upper respiratory illness to severe disseminated infection that could affects the bones, joints, skin, central nervous system, and the gastrointestinal tract. Previous reports of a positive stool culture in the setting of disseminated CM are extremely rare. Herein, we descri...

Sir, Six main clinical forms of porokeratosis are recognized: classical porokeratosis or porokeratosis of Mibelli, punctate palmoplantar porokeratosis, linear porokeratosis (LP), disseminated superficial porokeratosis, disseminated superficial actinic porokeratosis (DSAP), and disseminated palmoplantar porokeratosis (1). The coexistence of more than one form in a single individual is infrequent...

Disseminated nocardiosis is a well-described infection occurring in immunosuppressed individuals. Of the several species of Nocardia, Nocardia farcinica is being increasingly recognized as a pathogen capable of causing severe systemic disease. Described here is a case of disseminated nocardiosis with involvement of the brain, eyes, lymph nodes, and lung with biopsy-proven N. farcinica, with a d...

BACKGROUND Disseminated cutaneous herpes zoster in healthy persons is uncommon, though it has been described in immunocompromised patients. CASE PRESENTATION We describe a case of disseminated cutaneous herpes zoster in an elderly man with no apparent immunosuppressive condition. The patient was treated successfully with intravenous Acyclovir. CONCLUSION We suggest that disseminated zoster ...

Measurement bias has been defined as a violation of measurement invariance. Potential violators-variables that possibly violate measurement invariance-can be investigated through restricted factor analysis (RFA). The purpose of the present paper is to investigate a Bayesian approach to estimate RFA models with interaction effects, in order to detect uniform and nonuniform measurement bias. Beca...