Pelizaeus-Merzbacher disease (PMD) can now be defined as an X-linked recessive leukodystrophy that is caused by a mutation in the proteolipid protein (PLP) gene on chromosome Xq22. The most common mutation is gene duplication followed in frequency by missense mutations, insertions, and deletions. The clinical spectrum ranges from severe neonatal cases to relatively benign adult forms and X-link...

Prenatal exposure to maternal depression is common and puts offspring at risk for developing a range of neuropsychiatric disorders. Despite its prevalence and adverse associations, neurobiological processes by which prenatal maternal depression (PMD) confers risk remain poorly understood. Maternal mood and fetal behavior were assessed between 34 and 37 gestational weeks. Using resting-state fun...

BACKGROUND To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders. MATERIAL AND METHODS Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls). EBV DNA salivary analysis was performed by PCR. RESUL...

PURPOSE To report an unusual presentation of pellucid marginal degeneration (PMD). CASE REPORT A 57-year-old man with history of corneal ectasia experienced acute hydrops and spontaneous corneal perforation in his right eye. Examination revealed PMD in both eyes. After initial treatment with cyanoacrylate adhesive and a bandage contact lens, therapeutic penetrating keratoplasty was undertaken...

A temperature-compensated material of fiber Bragg grating (FBG), which has negative thermal -expansion coefficient has been presented. The temperature coefficient of FBGs’ center wavelength is less than 0.0005 nm/°C after three-layer-structure temperature-compensated package under tension. For the first time, PMD of FBG with and without temperature compensation has been detailedly studied and m...

The parieto-frontal circuit underlying grasping, which requires the serial involvement of anterior intraparietal area (aIPs) and ventral premotor cortex (PMv), has been recently extended enlightening role dorsal (PMd). supplementary motor (SMA) also suggested to encode grip force for grasping actions; furthermore, both PMd SMA are known play a crucial in imagery. Here, we aimed at assessing dyn...

Two high-PMD long distance routes were characterized and used to test an optical polarization mode dispersion compensator (PMDC) under field conditions. For this trial, 110 km routes with mean PMD values of 25 and 26.5 ps were provisioned with commercial WDM transport equipment and tested for several weeks. The route was comprised of three spans of characterized fiber that followed railroad tra...

BACKGROUND According to Warburg's effect, the rate of glycolysis increases in cancerous cells. This will increase overall levels of pyruvic acid. The present on-going study was conducted to estimate the levels of pyruvic acid in saliva and serum in normal, oral PMD subjects. MATERIAL AND METHODS A total of 50 subjects in healthy, PMD of the oral cavity individuals were selected based on clini...

The left dorsal premotor cortex (PMd) is thought to play a dominant role in the selection of movements made by either hand. We used transcranial magnetic stimulation to study the functional connectivity of the left PMd and right primary motor cortex (M1) during an acoustic choice reaction time (RT) task involving contraction of the thumb and forefinger. The facilitatory and inhibitory pathways ...

Evidence indicates the involvement of the rostral part of the dorsal premotor cortex (pre-PMd) in executive processes during working memory tasks. However, it remains unclear what the executive function of pre-PMd is in relation to that of the dorsolateral prefrontal cortex (DLPFC) and how these two areas interact. Using functional magnetic resonance imaging (fMRI), brain activity was examined ...