Disassembly sequence planning at the early conceptual stage of design leads to enormous benefits including simplification of products, lower assembly and disassembly costs, and design modifications which result in increased potential profitability of end-of-life salvaging operations. However, in the early design stage, determining the best disassembly sequence is challenging. First, the require...

The mechanisms that govern synapse formation and elimination are fundamental to our understanding of neural development and plasticity. The wiring of neural circuitry requires that vast numbers of synapses be formed in a relatively short time. The subsequent refinement of neural circuitry involves the formation of additional synapses coincident with the disassembly of previously functional syna...

This paper considers a Disassembly Line Balancing Problem (DLBP) under uncertainty. Disassembly task times are assumed to be random variables with known probability distributions. To deal with this uncertainty, a stochastic program is developed. It both chooses the best disassembly alternative for an end of life product and assigns the corresponding disassembly tasks to the workstations of the ...

The authors propose the implementation of hybrid Fuzzy Logic-Genetic Algorithm (FL-GA) methodology to plan the automatic assembly and disassembly sequence of products. The GA-Fuzzy Logic approach is implemented onto two levels. The first level of hybridization consists of the development of a Fuzzy controller for the parameters of an assembly or disassembly planner based on GAs. This controller...

Several bacterial pathogens hijack the actin assembly machinery and display intracellular motility in the cytosol of infected cells. At the cell cortex, intracellular motility leads to bacterial dissemination through formation of plasma membrane protrusions that resolve into vacuoles in adjacent cells. Here, we uncover a crucial role for actin network disassembly in dissemination of Listeria mo...

Both tropical and temperate species are responding to global warming through range shifts, but our understanding of the consequences of these shifts for whole communities is limited. Here, we use current elevational range data for six taxonomic groups spanning 90° in latitude to examine the potential impacts of climate-driven range shifts on community change, or 'disassembly', across latitude. ...

Continuous cycles of nucleocytoplasmic transport require disassembly of transport receptor/Ran-GTP complexes in the cytoplasm. A basic disassembly mechanism in all eukaryotes depends on soluble RanGAP and RanBP1. In vertebrates, a significant fraction of RanGAP1 stably interacts with the nucleoporin RanBP2 at a binding site that is flanked by FG-repeats and Ran-binding domains, and overlaps wit...

The supramolecular self-assembly and disassembly that are responsive to external stimuli are of critical importance to the design and synthesis of functional supramolecular materials. In this work, we performed a coarse-grained molecular dynamics study of photo-controlled assembly and disassembly on a timescale of ten microseconds. The spontaneous assembly of cis-AzoC10, trans-AzoC10, and cis-A...

Abstract In order to have a sustainable disassembly process, successful decision-making based on reliable and up-to-date information should be made while taking into consideration sustainability indicators. this context, The aim of paper is introduce decision support system knowledge digital twin in help stakeholders choose the most scenario .In research, firstly, we presented state art twin, m...