Scrub typhus is a potentially fatal, febrile disease prevalent in rural Asia. The etiological agent, Orientia tsutsugamushi, is transmitted to humans by the bite of a larval trombiculid mite. No current diagnostic test is sufficiently practical for use by physicians working in rural areas. A new dipstick test using a dot blot immunoassay format has been developed for the serodiagnosis of scrub ...

Dipstick urinalysis is an informative, quick, cost-effective and non-invasive diagnostic tool that is useful in clinical practice for the diagnosis of urinary tract infections (UTIs), kidney diseases, and diabetes. We used dipstick urinalysis as a hands-on microbiology laboratory exercise to reinforce student learning about UTIs with a particular focus on cystitis, which is a common bacterial i...

Hematuria is a common finding in primary care practice. Causes of significant hematuria include urinary tract infection, urolithiasis, malignancies, benign prostatic hyperplasia, and nephropathies. Hematuria is identified by taking a patient history and by performing a routine urine dipstick test. If a patient has a history of gross hematuria and/or a positive urine dipstick test, he or she ...

Designing easy-to-use biosensors for trace metal ions in the environment is of considerable importance as these metal ions are large in number, small in quantity and high in toxicity. Metal-specific DNAzymes, functional DNA molecules that can catalyze a reaction in the presence of a particular metal ion, have emerged as a new class of metal-ion sensors because DNAzymes with desired metal specif...

The examination of. urine specimens constitutes a major portion of the work of a clinical microbiology laboratory. Although the prevalence of urinary tract infection varies for different patient populations, most urine specimens are culture negative. In this laboratory only 12% of paediatric urines show evidence of urinary tract infection. The availability of a rapid reliable screening test for...

A short cut review was carried out to establish whether negative dipstick urine analysis is sensitive enough to rule out urinary tract infection (UTI) in adults with urinary symptoms. Altogether 75 papers were found using the reported search, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, ...