BACKGROUND Cardiac amyloidosis due to familial amyloid polyneuropathy (FAP) includes restrictive cardiomyopathy, thickened cardiac walls, conduction disorders and cardiac denervation. Impaired blood pressure variability has been documented in FAP related to the Val30Met mutation. AIMS To document blood pressure variability in FAP patients with various mutation types and its relationship to th...

The mechanisms by which Cordilleran plutons are emplaced vary widely. However, the present authors have examined a series of plutons ranging from 2–35 km emplacement depth that have many common features, which suggest that downward transport of host rock is the most important mechanism during magma ascent and pluton emplacement. Many of these Cordilleran plutons preserve gently dipping, unfault...

-Heterogeneous fault motion of the 1993 Hokkaido Nansei-Oki earthquake is studied by using seismic, geodetic and tsunami data, and the tsunami generation from the fault model is examined. Seismological analyses indicate that the focal mechanism of the first 10 s, when about a third of the total moment was released, is different from the overall focal mechanism. A joint inversion of geodetic dat...

The first and most important step in processing data in transversely isotropic (TI) media for which velocities vary with depth is parameter estimation. The multilayer normal-moveout (NMO) equation for a dipping reflector provides the basis for extending the TI velocity analysis of Alkhalifah and Tsvankin to vertically inhomogeneous media. This NMO equation is based on a root-mean-square (rms) a...

BACKGROUND/AIMS Little is known about the effect of twice daily administration of same dose of ACE inhibitor and ARB on the diurnal/nocturnal blood pressure (BP) ratio. We aimed to assess the effect of two widely used long-acting drugs: perindopril and losartan in the treatment of hypertension comparing the once-daily (evening) vs. twice-daily (morning and evening) administration with the same ...

This study developed models to predict lactic acid concentration, dipping time, and storage temperature combinations determining growth/no-growth interfaces of Listeria monocytogenes at desired probabilities on bologna and frankfurters. L. monocytogenes was inoculated on bologna and frankfurters, and 75 combinations of lactic acid concentrations, dipping times, and storage temperatures were tes...

The morning surge in blood pressure (BP) coincides with increased cardiovascular (CV) events. This strongly suggests that an altered circadian rhythm of BP plays a crucial role in the development of CV disease (CVD). A disrupted circadian rhythm of BP, such as the non-dipping type of hypertension (i.e., absence of nocturnal BP decline), is frequently observed in metabolic disorders and chronic ...