نتایج جستجو برای: dimethylaniline
تعداد نتایج: 361 فیلتر نتایج به سال:
Although the presence of skatole in decomposing protein materials and in feces has frequently been reported, very rarely have microorganisms been shown to form skatole in pure culture. Two species of the genus Clostridium have been described as producing skatole: Clostridium skatol Fellers and Clough (J. Bacteriol., 10, 130, 1925), which had been characterized earlier by Fellers (Abstr. Bacteri...
Microsomes isolated from Spodoptera frugiperda (Sf)9 cells infected with human flavin-containing monooxygenase (FMO)1 recombinant baculovirus catalyzed the NADPH- and O2-dependent oxidation of methimazole, thiourea, and phenylthiourea. However, there was no detectable activity with 1,3-diphenylthiourea or larger thiocarbamides. Microsomes from control Sf9 cells were devoid of methimazole or thi...
BACKGROUND Carcinogenic aromatic amines derived from hair dyes have recently received new attention. One of these is ortho (o)-toluidine, which is classified as carcinogenic to humans. OBJECTIVES To clarify exposure of hairdressers to potentially carcinogenic aromatic amines, including o-toluidine. METHODS We measured eight potentially carcinogenic aromatic amines in the blood of 295 hairdr...
Characterization and Structure-Function Studies of Human Liver Flavin Monooxygenase Isozyme 3 (FMO3)
45 Abstract: The activity of the flaving-containing monooxygenase (FMO EC 1.14.13.8) can be modulated by a number of nitrogencontaining compounds in a manner that is both isoform and effector-dependent. We showed that the direction (activation or inbihiton) and extent of modulation can also be dependent on substrate concentration. The native human liver FMO3 and arg 433 mutant FMO3 catalyze the...
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