Numerous agents can induce the terminal differentiation of leukemia cells in vitro, and this action has been found to be of therapeutic value in the treatment of acute promyelocytic leukemia. The proximal site of action of the prototypical chemical inducer of differentiation, dimethyl sulfoxide (DMSO), is not known. In this study, DMSO was found to rapidly cause a 45% to 85% reduction in the sp...

BACKGROUND, AIM The aim of this study was to investigate the effects of dimethyl sulfoxide (DMSO) on the acute phase of experimental corrosive esophageal burns. MATERIALS AND METHODS Fifty male rats were allocated into five groups (control, acid burn, alkali burn, acid burn + DMSO and alkali burn + DMSO) of ten rats each. Acid and alkali burns were creating by burning the distal esophagus wit...

Dimethyl sulfoxide (DMSO) is widely used as a solvent or vehicle for biological studies, and for treatment of specific disorders, including traumatic brain injury and several forms of amyloidosis. As Alzheimer's disease (AD) brains are characterized by deposits of β-amyloid peptides, it has been suggested that DMSO could be used as a treatment for this devastating disease. AD brains are also ch...

This study reexamined the possibility of improving separation binary azeotropic mixture containing tetrahydrofuran (THF) and ethanol from previous work ( J Chem Technol Biotechnol 2015; 90: 1463–1472) that rely on extractive distillation (ED) using ethylene glycol (EG) as solvent. Here, dimethyl sulfoxide (DMSO) is proposed an alternative solvent for ED, its feasibility preliminary screened com...

Three different organic solvents (dimethylacetamide (DMAc), dimethylformamide (DMF), and dimethyl sulfoxide (DMSO)) were used to improve the solubility of LiNO 3 in a standard carbonate-based electrolyte with lithium difluoro(oxalato)borate (LiDFOB) as salt. Together, LiDFOB organic-solvent solubilized preferentially reduce on surface silicon-containing anodes create an SEI rich oxalates, nitra...

Rechargeable zinc batteries (RZBs) are of immense interest as low-cost and sustainable energy storage devices. However, formation Zn dendrites, corrosion, undesired side reactions in aqueous electrolytes well the use costly fluorinated salts organic electrolytes, have hindered commercialization RZBs. In this work, a cost-efficient environmentally friendly, non-aqueous electrolyte comprised dicy...

Dimethyl sulfoxide (DMSO) is frequently utilized as a solvent in toxicological and pharmaceutical investigations. It is therefore important to establish the cellular and molecular targets of DMSO in order to differentiate its intrinsic effects from those elicited by a compound of interest. We performed a genome-wide functional screen in Saccharomyces cerevisiae to identify deletion mutants exhi...