statement of problem: glucocorticoid-induced osteoporosis is characterized by a decrease in osteoblast numbers and a marked impairment of new bone formation. purpose: the ain of present study was to evaluate the effect of methylprednisolone acetate on bone metabolism and bone mineral density in rats. materials and methods: eighteen male sprague dawley rats (8 weeks old, weighting 180 gm) were r...

lead is known to be a potent neurotoxin that can cause seizure activity in humans and animals. also, epileptic type convulsion is a known complication of hypothyroidism. this study was performed to determine the effect of propylthiouracil (ptu)-induced hypothyroidism and chronic lead exposure on pentylenetetrazol (ptz)-induced kindling parameters. the test was carried out by using male albino r...

chamaemelum nobile (asteraceae) commonly known as 'roman chamomile' is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. the present study was carried out to investigate the anticancer as well as apoptotic activity of ethyl acetate fraction of c. nobile on different cancerous cell lines. the cells were treated with varyi...

The objective of this study was to evaluate the effect of dietary supplements with lead acetate and aluminosilicates (ATN) on antioxidative enzyme activities and lipid peroxidation of the heart and skeletal muscle tissues of broiler chickens. Broilers were allotted to four diets including the control group, the Pb group, the aluminosilicate-ATN (antitoxic nutrient) group and the Pb+ATN group, i...