The nematode Caenorhabditis elegans shows a high degree of conservation of molecular pathways related to human disease, yet is only 1-mm long and can be considered as a microorganism. Because of the development of a simple but systematic RNA-interference (RNAi) methodology, C. elegans is the only metazoan in which the impact of "knocking-down" nearly every gene in the genome can be analyzed in ...

OBJECTIVE to assess the usability of a digital learning technology prototype as a new method for minimally invasive monitoring of intracranial pressure. METHOD descriptive study using a quantitative approach on assessing the usability of a prototype based on Nielsen's ten heuristics. Four experts in the area of Human-Computer interaction participated in the study. RESULTS the evaluation del...

In the 21st century, which is called digital age, documentary cinema has undergone many changes in terms of both content and form. Apart from being a display medium, interfaces screens have become spheres where narrative constructed. Thus, production viewing dimensions films changed traditional documentaries started to be replaced by interactive documentaries. these documentaries, director beco...

Rendering high contrast scenes on display devices with limited dynamic range is a challenging task. Two groups of algorithms have emerged to take up this challenge: tone mapping operators (TMOs) and more recently exposure fusion (EF) techniques. While several formal evaluation studies comparing TMOs exist, no formal evaluation has yet been performed that compares EF techniques with each other o...

Digital detector arrays are used for industrial radiography and cone beam CT. Scattering and beam hardening artifacts reduce the achievable contrast sensitivity and can severely limit the size of the part to be scanned or require large amounts of shielding to block scatter outside the inspection area of interest. Varian’s image processing toolkit contains a set of dll’s that can easily be deplo...

The loss of longitudinal connectivity in regulated rivers, both up- and downstream, has been detrimental for biodiversity worldwide. While progress made regarding upstream fish passage solutions, many questions remain unanswered downstream alternatives. To address these knowledge gaps, we used Atlantic salmon (S. salar) smolts to experimentally assess the guidance efficiency rates produced by s...