The relevance of medical ethics to daily practice should be obvious to all doctors, but the relationship between 'ethics and practice' raises many complex moral issues. 'Medical ethics is not a new subject, but a vital aspect of all medical practice, the implications of which must be made explicit throughout medical education'.' The key word is 'explicit', because morality is a serious and abst...

Clustering techniques are often used to cluster grouping text documents. Modeling and graph-based representation of the document clustering process can be done by using algorithms Document Index Graph (DIG). This study aims to implement the DIG algorithm for designing the structure digraphs used for graphical representation of web document clustering process. The data used is the REUTERS-21578 ...

Fish venom remains a virtually untapped resource. There are so few fish toxin sequences for reference, which increases the difficulty to study toxins from venomous fish and to develop efficient and fast methods to dig out toxin genes or proteins. Here, we utilized Chinese yellow catfish (Pelteobagrus fulvidraco) as our research object, since it is a representative species in Siluriformes with i...

Previous studies have shown that Gardnerella vaginalis can utilize iron-loaded human lactoferrin as a sole source of iron. In this study, G. vaginalis cells were shown to bind digoxigenin (DIG)-labeled human lactoferrin in a dot blot assay. Using the DIG-labeled human lactoferrin, a 120-kDa human lactoferrin-binding protein was detected by Western blot analysis of G. vaginalis proteins. The lac...

Most bioscientists need to report mean values, yet many have little idea of how many digits are significant, and at what point further digits are mere random junk. Thus a recent report that the mean of 17 values was 3.863 with a standard error of the mean (SEM) of 2.162 revealed only that none of the seven authors understood the limitations of their work. The simple rule derived here by experim...

Software bugs are a persistent feature of daily life—crashing web browsers, allowing cyberattacks, and distorting the results of scientific computations. One approach to improving software uses program invariants—mathematical descriptions of program behaviors—to verify code and detect bugs. Current invariant generation techniques lack support for complex yet important forms of invariants, such ...

The analysis of differential gene expression has become increasingly important in recent years. Typically, differentially expressed genes are identified in a primary screening procedure, yielding candidate genes whose differential expression has to be verified. We provide a highly sensitive, efficient and nonradioactive differential screening procedure to analyze numerous candidate genes in a s...

Pyrazino compounds such as quinoxalines are 1,4-diazines with widespread occurrence in nature. Quinolin-8-amines are isomerically related and valuable scaffolds in organic synthesis. Herein, we present intramolecular main group metal Lewis acid catalyzed formal hydroamination as well as hydroarylation methodology using mono-propargylated aromatic ortho-diamines. The annulations can be conducted...

Metal carbenes are often proposed as reactive intermediates in the late transition metal-catalysed transformations of alkynes. Owing to their high reactivity, however, isolation and structural characterization of metal carbene intermediates in these transformations has remained unknown. Herein, we report the isolation of two acyclic gold and copper carbene intermediates in either Au(I)- or Cu(I...

Dependency parses are an effective way to inject linguistic knowledge into many downstream tasks, and many practitioners wish to efficiently parse sentences at scale. Recent advances in GPU hardware have enabled neural networks to achieve significant gains over the previous best models, these models still fail to leverage GPUs’ capability for massive parallelism due to their requirement of sequ...