BACKGROUND It is well known that some trace elements such as zinc and copper play a significant role in many forms of hair loss. However, the effect of zinc and copper in the pathogenesis of hair loss is still unknown. OBJECTIVE The purpose of this study is to evaluate the zinc and copper status in each of four types of hair loss. METHODS A study was carried out with 30 health controls and ...

Loss of sensory hair cells of the inner ear due to aminoglycoside exposure is a major cause of hearing loss. Using an immortalized multipotent otic progenitor (iMOP) cell line, specific signaling pathways that promote otic cell survival were identified. Of the signaling pathways identified, the PI3K pathway emerged as a strong candidate for promoting hair cell survival. In aging animals, compon...

Vogt-Koyanagi-Harada syndrome (VKH syndrome) is a rare granulomatous inflammatory disease that affects melanocyte pigment-producing melanocytes and primarily pigmented structures such as the eyes, inner ear, skin, meninges, hair. VKT an autoimmune disease, which CD4 + Th1 T lymphocyte-mediated aggression to melanocytes. Melanin usually gives color hair eyes. also found in retina, where it plays...

A nswer: Hair provides no vital function but does protect the surface of the skin, conserves body heat, and contributes to self-image. Hair is associated with femininity (e.g., long hair) and masculinity (e.g., facial hair) and, for many, closely associated with sexuality (DeVillez, 2003; Ehmann, Sheehan, & Decker, 1991). Although not considered life threatening, chemotherapy-induced hair loss ...

BACKGROUND Platelet-rich plasma (PRP) is an autologous concentration of human platelets contained in a small volume of plasma with haemostatic and tissue repairing effects. Being enriched by various growth factors, PRP has become the focus of attention in numerous fields of medicine. Androgenic alopecia (AGA) is a common chronic hair loss disorder, characterised by progressive hair loss. Despit...

BACKGROUND Androgens are thought to have an adverse effect on female scalp hair growth. However, our clinical experience of androgen replacement therapy in women with androgen deficiency, in which hair loss was seldom reported, led us to question this concept. OBJECTIVES To evaluate the effect of subcutaneous testosterone therapy on scalp hair growth in female patients. METHODS A total of 2...

Hair is a very important for our self-confidence as well as a very important part of appearance and self-concept. It reflects our personality and hair loss or hair damages are considered aesthetic imperfections and social handicap. Outward part of the hair is a "hair shaft" keratin fiber structure sensible to external effects whether they are mechanical, physical or chemical. Excessive sun expo...

Hair has always played an important role in the history of mankind. Egyptian hieroglyphics are testimony of the paramount importance of hair for this ancient civilization, not only because of the visual effect, but also because of the erotic symbolism connected with hair. For the ancient Romans hair was not only a question of fashion but was used as a symbol of beauty, virility, class and intel...

The classic view of sensorineural hearing loss (SNHL) is that the "primary" targets are hair cells, and that cochlear-nerve loss is "secondary" to hair cell degeneration. Our recent work in mouse and guinea pig has challenged that view. In noise-induced hearing loss, exposures causing only reversible threshold shifts (and no hair cell loss) nevertheless cause permanent loss of >50% of cochlear-...

Female pattern hair loss (FPHL) is the most common hair loss disorder in women. Initial signs may develop during teenage years leading to a progressive hair loss with a characteristic pattern distribution. The condition is characterized by progressive replacement of terminal hair follicles over the frontal and vertex regions by miniaturized follicles, that leads progressively to a visible reduc...