Number of Papers published in peer-reviewed journals: Number of Papers published in non peer-reviewed journals: Final Report: High Stability Metal-Protein Interactions Evaluated by Microcalorimetry Report Title Isothermal titration calorimetry (ITC) is a microcalorimetry technique used to study interactions between biomolecules and ligands in aqueous solution. This ARO equipment grant was provi...

Two novel coordination polymers [Ag16(SO4)8][Ag4(SO4)2]3(L1)12·nH2O (n = 72) (1) and [Ag10(SO4)5(L2)4(H2O)2]·8H2O (2) based on conformationally variable oligo-α-heteroarylsulfanyl ligands 2-(pyrazin-2-ylthio)-6-(pyridin-2-ylthio)pyrazine (L1) or 2,6-bis(pyrazin-2-ylthio)pyrazine (L2) and sulfate-templated high-nuclearity Ag(I) clusters as structure-building units (SBUs) have been synthesized un...

Differential scanning calorimetry (DSC) and isothermal calorimetry have been applied extensively to the analysis of light metals, especially Al based alloys. Isothermal calorimetry and differential scanning calorimetry are used for analysis of solid state reactions, such as precipitation, homogenisation, devitrivication and recrystallisation; and solid–liquid reactions, such as incipient meltin...

Proper characterization is an important aspect of any dosage form design. The objective of this work was to characterize tannate salt and hydrochloride salt of diphenhydramine. As a part of characterization studies, Differential scanning calorimetry was used to investigate thermal effects and nature of salts, supported by X-ray powder diffraction. Scanning electron microphotographs was used to ...

Trans-dehydrocrotonin has antiulcerogenic and antitumor activities. A complex of beta-cyclodextrin with dehydrocrotonin was developed to improve the delivery of dehydrocrotonin. Complex in solid state was evaluated using X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA) and scanning electron microscopy (SEM). X-ray diffraction and scanning elec...

A new synthetic approach to highly substituted triphenylboroxines 11 is described. Their mesomorphic properties were investigated by differential scanning calorimetry (DSC), polarizing optical microscopy (POM) and X-ray diffraction (SAXS, WAXS). The tris(3,4,5-trialkyloxy)phenyl functionalized derivatives 11b-e showed broad mesophases for a minimum alkyl chain length of C9. The phase widths ran...

Micrometre-sized water droplets were hyperquenched on a solid substrate held at selected temperatures between 150 and 77 K. These samples were characterized by differential scanning calorimetry (DSC) and X-ray diffraction. 140 K is the upper temperature limit to obtain mainly amorphous samples on deposition within 16-37 min. DSC scans of glassy water prepared at 140 K exhibit on heating an endo...