OBJECTIVE Iron therapy may reinforce intestinal inflammation by catalysing production of reactive oxygen species. The effects of oral ferrous fumarate and intravenous iron sucrose on clinical disease activity and plasma redox status were investigated in patients with inflammatory bowel disease (IBD). MATERIAL AND METHODS Nineteen patients with iron deficiency anaemia and Crohn's disease (11) ...

background: the present study was undertaken to study the larvicidal activity of different extracts of nerium ole- ander leaves, and post-treatment temperature- toxicity relationship of these extracts against culex pipiens. further, the most potent extract was used to evaluate its biological and genotoxic activities. methods: crude extracts of n. oleander leaves were prepared using water, chlor...

In this paper x, X, X1, X2 are sets. Let Y be a functional set. The functor DOMS(Y ) is defined by: (Def. 1) DOMS(Y ) = ⋃ {dom f : f ranges over elements of Y }. Let us consider X. We say that X is complex-functions-membered if and only if: (Def. 2) If x ∈ X, then x is a complex-valued function. Let us consider X. We say that X is extended-real-functions-membered if and only if: (Def. 3) If x ∈...

The blood flow changes in the optic nerve head in adult albino rabbits following intravenous administration of brovincamine fumarate, an improver of cerebral circulation and metabolism, were investigated employing the hydrogen clearance method. In the brovincamine fumarate (0.1 mg/kg)-administered group, the blood flow in the optic nerve head increased soon after injection and reached the maxim...

an efficient three-component reaction of dialkyl acetylendicarboxylates and 2-pyrrolidin in the presence of triphenylphosphine produces dialkyl 2-(2-pyrrolidin-n-yl)-3-(triphenylphosphanylidene)succinate. these phosphoranes undergo mild intramolecular wittig reaction to produce dialkyl (e)-2-(4,5-dihydro-3h-pyrrol-2-yl)fumarate in excellent yields.

Mutants of Escherichia coli K12 strain WGAS-GF+/LF+ were selected for their inability to use fumarate as terminal electron acceptor for supporting growth on glycerol or lactate in an atmosphere of H2 plus 5% CO2. Eighty-three mutants were grouped into seven different categories according to their ability to grow on different media and their ability to produce gas during glucose fermentation. En...

Fumarate reductase from Escherichia coli functions both as an anaerobic fumarate reductase and as an aerobic succinate dehydrogenase. A site-directed mutation of E. coli fumarate reductase in which FrdB Pro-159 was replaced with a glutamine or histidine residue was constructed and overexpressed in a strain of E. coli lacking a functional copy of the fumarate reductase or succinate dehydrogenase...