This experiment was conducted to investigate the effect of dietary supplementation with green tea extract on growth performance, meat quality and oxidative stability longissimus thoracis et lumborum (LTL) muscle in growing-finishing pigs. A total 16 crossbred pigs, half females males, were randomly assigned 2 treatments. lasted 9 weeks included grower finisher periods. The experimental diets ea...

The mammalian CNS is considered to be autonomous in lipid metabolism. Glial cells, in particular astrocytes, have been shown to be highly active in lipid synthesis and secretion. To determine the importance of astrocytes as lipid providers in the brain, we generated mice in which the sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) was deleted from astrocytes...

Aim: Objectives To evalate the differences in metabolic responses between dietary orotic acid and adenine in lipid profi les of serum and liver tissues. Methods: Rats were paired-fed 1.0 % orotic acid (orotic acid group) and 0.25 % adenine (adenine group) diets or a non-supplemented diet (control group) for 10 days. Serum lipid concentrations were measured using enzyme assay kits. Lipids of liv...

Methionine-choline-deficient (MCD) diets that cause steatohepatitis in rodents are typically enriched in polyunsaturated fat. To determine whether the fat composition of the MCD formula influences the development of liver disease, we manufactured custom MCD formulas with fats ranging in PUFA content from 2% to 59% and tested them for their ability to induce steatohepatitis. All modified-fat MCD...

Leptin is a 16 kDa protein synthesized and secreted primarily from adipocytes. Leptin acts centrally to regulate appetite and energy expenditure and has peripheral effects to coordinate whole-body energy metabolism. Leptin acts as an energy balance and nutrient sensor; its expression and function are regulated by endocrine and dietary factors. Leptin regulates lipid metabolism, specifically lip...

BACKGROUND Although dietary ketogenic essential amino acid (KAA) content modifies accumulation of hepatic lipids, the molecular interactions between KAAs and lipid metabolism are yet to be fully elucidated. METHODOLOGY/PRINCIPAL FINDINGS We designed a diet with a high ratio (E/N) of essential amino acids (EAAs) to non-EAAs by partially replacing dietary protein with 5 major free KAAs (Leu, Il...

Two experiments were conducted with golden Hubbard pullet chicks to investigate the replacement effects of locally prepared fish silage for imported meal in and layers' rations. Acidic neutral preparations concentrated either maize or cassava plus groundnut wheat offals, fed as a substitute meal. Results pullets showed good feed consumption all dietary treatments but efficiency was decreased (P...

Trout reared at 8 or 18 degrees C were fed twice a day almost to satiation with 1 of 3 experimental diets. The diets were formulated to contain the same levels of protein (43%, dry matter (DM) basis) and digestible energy (around 15 kJ/g DM), but different carbohydrate/lipid ratios 30:7 to 23:14). Time-course studies of nitrogen excretion and glycaemia were also carried out. After 12 weeks of f...