The American Physiological Society officially recognized the area of research in Water and Electrolyte Homeostasis (WEH) over 30 years ago when the Section of WEH was established. This minireview illuminates the importance of WEH research to the physiology community. By the narrowest definition, WEH research studies the regulation of body fluids; however, this research area is much broader and ...

T H E great majority of patients who This post-operative response affects undergo a surgical operation are able, many of the metabolic processes of the within a very short while, to return to a body, indeed probably more than we are normal intake of food and drink, so that, yet aware of, but . its most important with regard to fluid balance, they present effects are on the handling by the body ...

We compared the acid-base balance in broiler chickens provided diets containing 2 dietary electrolyte balances (DEB), and administered with either adrenocorticotropic hormone (ACTH) or saline solution. Diets were moderate (174 mEq/kg) or high (241 mEq/kg) DEB formulated by altering Na-K-Cl based on actual analysis. The experiment was designed as a split plot, with the main unit consisting of 4 ...

In metabolic balance studies the intake and excretion of sodium, potassium, and water were measured in spontaneously hypertensive rats (SHRs) of the Okamoto-Aoki strain and age-matched Wistar Kyoto rats (WKYs) that were 3 through 13 weeks of age. While fed their usual chow, young SHRs exhibited differences in excretion as compared to WKYs consuming essentially equivalent amounts of food and wat...

Six patients with jejunostomies and residual jejunal lengths of 105 to 250 cm took the same food and water each day for eight study days. In random order, three methods of salt replacement were tested, each over 48 hours, against a period without added salt. During the three test periods the patients took 120 mmol of sodium chloride daily, as salt in gelatine capsules, as an isotonic glucose el...

Nitric oxide is a pronatriuretic and prodiuretic factor. The highest renal NO synthase (NOS) activity is found in the inner medullary collecting duct. The collecting duct (CD) is the site of daily fine-tune regulation of sodium balance, and led us to hypothesize that a CD-specific deletion of NOS1 would result in an impaired ability to excrete a sodium load leading to a salt-sensitive blood pre...

White-nose syndrome is devastating North American bat populations but we lack basic information on disease mechanisms. Altered blood physiology owing to epidermal invasion by the fungal pathogen Geomyces destructans (Gd) has been hypothesized as a cause of disrupted torpor patterns of affected hibernating bats, leading to mortality. Here, we present data on blood electrolyte concentration, haem...