There are many diseases related to ion channels. Mutations in muscle voltage-gated sodium, potassium, calcium and chloride channels, and acetylcholine-gated channel may lead to such physiological disorders as hyper- and hypokalemic periodic paralysis, myotonias, long QT syndrome, Brugada syndrome, malignant hyperthermia and myasthenia. Neuronal disorders, e.g., epilepsy, episodic ataxia, famili...

This chapter presents a bibliographic review of asbestos-related diseases. The latest diagnostic, radiological, computed tomography and lung function aspects of benign pleural disease, asbestosis, occupational lung cancer and mesothelioma are discussed.

The greatest challenge to health in the Region is the premature death and physical and mental disability resulting diseases as obesity, diabetes, cardiovascular disease, certain types of cancer, and osteoporosis. Most of those diseases are aptly labeled now Diet-related Chronic Diseases (DCD) as they are associated to lack of physical activity and poor diets, including the consumption of foods ...

Liver diseases related to pregnancy may be associated with preeclampsia (liver dysfunction related to preeclampsia; hemolysis, elevated liver enzymes, and low platelets with or without preeclampsia [HELLP syndrome]; and acute fatty liver of pregnancy) or may not involve preeclampsia (hyperemesis gravidarum and intrahepatic cholestasis of pregnancy). Liver diseases associated with pregnancy have...

There are at least eight categories of cilia in the human body and malfunctioning of any one or several of them will have different consequences for the patient. A genetic error of the respiratory cilia (9 + 2) is the cause of the airways disease named immotile-cilia syndrome (or PCD), whereas defective ependymal cilia (9 + 2) carries an increased risk of hydrocephalus. When the so-called nodal...

There are many evidences confirming that a_ BMI more than 25 will significantly increase the risk of cardiovascular problems and related diseases. BMI more than 30 will dramatically raise mortality rate. An increase in BMI will lead to an increase of mean blood pressure and blood cholestrol, and a decrease in HDL levels. In men with morbid obesity the risk of hypertemion and/or elevated cholest...

Background: Obesity as the excessive accumulation of adipose in adipocytes has still remained equivocal. Since diets contain many components to prevent from or promote diseases, assessing effects of the whole diet on health can be more practical. The purpose of this study was to investigate the association between quality of diets through healthy eating index (HEI), and body composition paramet...

Asbestosis is defined as diffused interstitial fibrosis of the lung, as a consequence of exposure to asbestos fibres, often associated with pleural plaques. Diagnosis of asbestosis, according to the American Thoracic Society (2004) is based on the following criteria: 1. hystopathological or imaging demonstration of structural alterations compatible with asbestos-related disease; 2. previous asb...

■ ■ Work-related Asthma: Asthma may be caused or made worse by work. People with work-related asthma often have more symptoms at work and improve away from work (on weekends and vacations). Many different exposures at work can cause occupational asthma. In addition, people who already have asthma may have work-exacerbated asthma due to asthma triggers at work, such as irritants, allergens, and ...