Abstract Study question How does the gene expression profile of epithelium cells differ between deep infiltrating endometriosis (DIE) and adenomyosis (FA)? Summary answer The epithelial from DIE reveals a significant upregulation PI3K-pathway downregulation RAS-pathway compared to FA. What is known already Both FA, are histologically considered benign but have features malignant diseases, such ...

Abstract Study question To assess the effect of oral relugolix combination therapy (Relugolix-CT) in subgroup women with endometriosis-associated pain who received prior first-line hormonal treatment. Summary answer Relugolix-CT significantly reduced dysmenorrhoea and non-menstrual pelvic (NMPP) through 24 weeks What is known already ESHRE recommends contraceptives or progestogens as for endome...