We provide a general method for producing a variety of small, complex electrode arrays based on injection molds produced using computer-aided drafting and machining (CAD-CAM) procedures and a novel method for connecting to the very fine electrical leads associated with the individual contacts of such arrays. Cat-sized cochlear electrode arrays with up to eight contacts were built according to t...

We report that chloromethyl-X-rosamine (MitoTracker Red), a mitochondrion-selective fluorescent probe, has a strong photosensitising action. Photoirradiation of intact cells loaded with chloromethyl-X-rosamine induces depolarisation of the inner mitochondrial membrane and swelling of mitochondria, subsequently resulting in apoptosis. We have studied human osteosarcoma 143B TK-(rho+) cells and t...

Some issues; leakage, tunneling currents, boron diffusion are threatening SiO2 to be used as a good gate dielectric for the future of the CMOS (complementary metal- oxide- semiconductor) transistors. For finding an alternative and novel gate dielectric, the NiO (Nickel oxide) and PVA (polyvinyl alcohol) nano powders were synthesized with the sol-gel method and their nano structural p...

Different variants of stochastic leaky integrate-and-fire model for the membrane depolarisation of neurons are investigated. The model is driven by a constant input and equidistant pulses of fixed amplitude. These two types of signal are considered under the influence of three types of noise: white noise, jitter on interpulse distance, and noise in the amplitude of pulses. The results of comput...

Here we describe an improved sensor with reduced pH sensitivity tethered to adenylyl cyclase (AC) 8. The sensor was used to study cAMP dynamics in the AC8 microdomain of MIN6 cells, a pancreatic β-cell line. In these cells, AC8 was activated by Ca(2+) entry through L-type voltage-gated channels following depolarisation. This activation could be reconstituted in HEK293 cells co-expressing AC8 an...

The dielectric and relaxation parameters of a binary system of edible oils, containing unsaturated fats namely mustard oil and coconut oil/ground nut oil/linseed oil in different proportions by volume are measured at different frequencies and a constant temperature (40°C). It is realized that at the given temperature, the dielectric constant of prepared samples at microwave frequency increases ...

A dielectric measurement for the aqueous solutions at lower frequencies (20Hz to 2MHz) has been carried out in frequency domain using Agilient Precision LCR meter (E4980A). The dielectric permittivity spectra of over entire concentrations with aqueous solutions are measured at 25 ̊C. From observed spectra, static dielectric constants (ε0) have been determined. Dielectric Spectroscopy is especial...

Thus far, the measurement of dielectric properties of biological tissues has been achieved on the assumption that the biological tissues are homogeneous. In fact, most tissues should be heterogeneous because there are many small structures included in these tissues, such as blood vessel, nerve fiber and so on. When the dielectric properties of these tissues are measured by conventional sensor, ...

An important part of the modelling process applied to vegetation effects is aimed at analysing the radio propagation modes and the identification of individual signal contributions to the scattered signal caused by various elements of the tree. The paper describes detailed studies aimed at the wideband characterisation of propagation mechanisms arising in single trees. It explores effects of ge...