Background and objectives: Severe burn damage and its consequences are life threatening which can complicate patients’ health. Burn damage increases reactive oxygen species (ROS) generation which leads to severe damage to tissues and is implicated in burn shock. Some medicinal and traditional plants are considered as safe, natural and inexpensive sources for treatment of differ...

This study aimed to investigate the effect of policresulen treatment with various concentrations on wound healing in buccal mucosa white rats (Rattus norvegicus) through macroscopically observation. The number 54 were divided into six groups concentration 36%, 10%, 5%, 1%, 0.3% and one control group. mucosal injury was made a 0.5 cm biopsy punch. conducted by dropped 2nd day until 5th after inj...

In this study, silk fibroin was extracted from cocoons of silkworms and fabricated into nonwoven mats by electrospinning method. A new model based on the group method of data handling (GMDH) and artificial neural network (ANN) was developed for estimation of the average diameter of electrospun silk fibroin nanofibers. In this regard, concentration, flow rate, voltage, distance, and speed of col...

AIMS To investigate if the amniotic membrane (AM) promotes epithelial migration while inhibiting stromal remodelling associated with corneal haze after excimer laser keratectomy. METHODS A wound 150 microm in depth and 6.0 mm in diameter was produced in 40 rabbits using an excimer laser. One eye was randomly chosen to be covered by the AM while the other eye served as a control. Epithelial wo...

wound healing in the skin depends upon the availability of appropriate trace metals as enzyme cofactors and structural components in tissue repair. the present study is a part of a series of experimental investigations to examine the influence of bentonite on skin wound healing. surgically induced skin wounds in 48 young adult male rats were exposed topically to bentonite (12 round wound and 12...

BACKGROUND Negative pressure wound therapy (NPWT) is believed to initiate granulation tissue formation via macro-deformation of the wound edge. However, only few studies have been performed to evaluate this hypothesis. The present study was performed to investigate the effects of NPWT on wound contraction and wound edge tissue deformation. METHODS Six pigs underwent median sternotomy followed...

background & aim: milk thistle [silybum marianum (l.) gaertn] is an annual or biennial plant, native to the mediterranean area, which has spread in north and south of iran. a fruit of milk thistle contains a relatively high amount (approx. 20%) of oil, which exhibits wound-healing, anti-burn, and hepatoprotective properties. experimental: in this research, a pot experiment was conducted usi...

PURPOSE The purpose of this study was to share our experience of transcatheter closure of small patent ductus arteriosus (PDA) by using an Amplatzer vascular plug (AVP). METHODS We reviewed the medical records of 20 patients who underwent transcatheter closure at Samsung Medical Center and Sejong General Hospital from January 2008 to August 2012. The size and shape of the PDAs were evaluated ...

Negative-pressure wound therapy has recently gained popularity in chronic wound care. This study attempted to explore effects of different negative pressures on epithelial migration in the wound-healing process. The electric cell-substrate impedance sensing (ECIS) technique was used to create a 5 x 10(-4) cm(2) wound in the Madin-Darby canine kidney (MDCK) and human keratinocyte (HaCaT) cells. ...