Twenty-four hour urinary albumin concentrations were measured in 113 (mean age 51.1 years) non-insulin-dependent (NIDDM) Nigerian diabetics (50 males, 63 females). A high prevalence of microalbuminuria (> or = 30 mg/24 hour) was observed in male (54%) as well as female diabetics (59%). Microalbuminuria was also observed in a high proportion of diabetics (52%) with a short duration (< 5 years) o...

To assess the effects of genetic predisposition of essential hypertension on early renal function in recent insulin-dependent diabetics, we studied inulin, para-aminohippuric, sodium, and lithium clearances in 69 unselected diabetics with (n = 20) and without (n = 49) a family history of essential hypertension. Despite similar metabolic control, glomerular filtration rate and mean arterial pres...

Cardiovascular morbidity and morality is higher in diabetics with proteinuria. The causative factors for such incidence are as yet not known. We studied lipid profiles among non-insulindependent diabetics with proteinuria who otherwise have normal blood urea and serum creatinine concentrations and compared the results with those who did not have proteinuria. Twenty four-hour protein estimations...

EARLIER trials at Whittington Hospital confirmed the hypoglycaemic effects of tolbutamide (Wolff, Stewart, Crowley and Bloom, 1956), phenformin (Hall, Crowley and Bloom, 1958) and chlorpropamide (Granville-Grossman, Crawford, Crowley and Bloom, 1959). Since the inception of oral therapy, more than 400 diabetics at this hospital have been successfully treated with these agents for more than thre...

AIM To compare corneal endothelial structure and central corneal thickness (CCT) between type II diabetics and non-diabetic control patients. To look for correlations between diabetic status and corneal findings. METHODS Hospital-based, observational study. 200 eyes (from 100 type II diabetic patients and 100 controls) were included. Specular microscopy and pachymetry were used to measure end...

A questionnaire-based cross-sectional study was carried out to assess the awareness of diabetes mellitus among rural and urban diabetics. After analyzing the awareness level of both populations, the urban diabetics were found to be more educated about diabetes. A 25-question survey was used to judge the awareness level of diabetes mellitus. A total of 240 diabetics were surveyed, 120 each from ...

plete revascularization could be achieved. Thus, it is very encouraging that, in the stent era, even in diabetics with multivessel disease after CABG, PCI may be contemplated as a reasonable treatment option when additional revascularization is required. The disturbing news is that overall, diabetics continue to fare much worse than non diabetics, with large increases in mortality at 3 years. T...

About a quarter of insulin dependent diabetics have low concentrations of the fourth component of complement (C4), and a low concentration of C4 is associated with diabetic microangiopathy. The variability of the expression of the C4 gene was compared in insulin dependent diabetics with and without microangiopathy and controls. Of the two genes coding for C4, the A gene (C4A) was not expressed-...

BACKGROUND Type 1 diabetic patients and non-diabetic patients were referred for evaluation for chronic exertional compartment syndrome (CECS) based on clinical examination and complaints of activity-related leg pain in the region of the tibialis anterior muscle. Previous studies using near-infrared spectroscopy (NIRS) showed greater deoxygenation during exercise for CECS patients versus healthy...

Introduction Cardiovascular magnetic resonance (CMR) is recommended in both NICE and ESC guidelines patients with new onset left ventricular systolic dysfunction (LVSD) to identify aetiology. In LVSD, type 2 diabetes associated increased prevalence of silent myocardial infarction (MI). We aimed investigate if MI LVSD are larger diabetic compared non-diabetic patients. Methods ...