A 53 year-old male diabetic presented with a month-old, painful ulcer with necrotic margins over the right thigh. Wound debridement was done twice and the ulcer showed recurrent growth of a white, cottony filamentous structure. Cutaneous mucormycosis was suspected and confirmed by histopathology and a culture isolate of Apophysomyces elegans . The patient was treated with liposomal amphotericin...

Modelling A Markov model was used to assess the clinical and economic outcomes associated with the two strategies under evaluation in a hypothetical cohort of patients with diabetic foot ulcers. The time horizon of the model was one year and the cycle length was one month. Patients entered the model with uninfected ulcers and, each month, moved across health states. The health states considered...

Modelling A Markov model was used to assess the clinical and economic outcomes associated with the two strategies under evaluation in a hypothetical cohort of patients with diabetic foot ulcers. The time horizon of the model was one year and the cycle length was one month. Patients entered the model with uninfected ulcers and, each month, moved across health states. The health states considered...

M a i n r e s u l t s 5 trials met the selection criteria. 3 trials compared hydrogel as a method of debridement with standard wound care (good wound care or gauze). 1 trial compared hydrogel with larval therapy. 1 trial compared surgical debridement with conservative care. In all 5 trials, the primary outcome was complete wound closure. Sample sizes ranged from 29 to 172 patients. In 4 trials,...

Background

Modelling A Markov model was used to assess the clinical and economic outcomes associated with the two strategies under evaluation in a hypothetical cohort of patients with diabetic foot ulcers. The time horizon of the model was one year and the cycle length was one month. Patients entered the model with uninfected ulcers and, each month, moved across health states. The health states considered...

Diabetic foot disease is a major health problem, which concerns 15% of the 200 million patients with diabetes worldwide. Major amputation, above or below the knee, is a feared complication of diabetes. More than 60% of non-traumatic amputations in the western world are performed in the diabetic population. Many patients who undergo an amputation, have a history of ulceration. Major amputations ...

BACKGROUND Although Diabetes mellitus is a major public health problem in the Middle East and North Africa (MENA) region with high rates of diabetic foot complications, there are only limited data concerning mortality among such a high risk group. Therefore, the main aim of the current study was to assess all-cause mortality and its related predictors among diabetic patients with and without di...

BACKGROUND Although monitoring foot skin temperatures has been associated with diabetic foot ulcer recurrence, no studies have been carried out to test the feasibility among European Caucasians. Moreover, the educational and/or motivational models that promote cognitive or psychosocial processes in these studies are lacking. Thus, we conducted a pilot randomized controlled trial to test the fea...