BACKGROUND Approximately one-third of individuals with type 2 diabetes mellitus will eventually develop diabetic nephropathy (DN). Impaired renal function in type 2 diabetics may also be secondary to non-diabetic renal disease (NDRD). NDRD in type 2 diabetics may occur alone in the absence of DN or may be superimposed on DN. Renal biopsy maybe indicated to establish the correct diagnosis and to...

UNLABELLED Aims/Introduction:  The present study investigated the frequency of mild anemia, which is not an indication of intensive therapy using drugs, in Japanese patients with type 2 diabetes mellitus and the association of mild anemia with diabetic complications. MATERIALS AND METHODS   This is a cross-sectional study of 1189 patients with type 2 diabetes mellitus. Anemia was defined as a...

OBJECTIVE To evaluate the gene expression of beta-trace protein in urine of diabetic patients, with no reduction in glomerular filtration rate, which was defined as below 60mL/min/1.73m2. METHODS Type 2 diabetes mellitus patients were recruited, and a group of non-diabetic individuals served as control. Beta-trace protein gene expression was analyzed by quantitative PCR. Blood samples were co...

BACKGROUND Abnormal endothelial function promotes atherosclerotic vascular disease in diabetes. Experimental studies indicate that disruption of endothelial insulin signaling, through the activity of protein kinase C-β (PKCβ) and nuclear factor κB, reduces nitric oxide availability. We sought to establish whether similar mechanisms operate in the endothelium in human diabetes mellitus. METHOD...

The aim of this study was to investigate the relationship between the number of teeth and diabetic retinopathy among Korean population.This was a retrospective analysis using data of total 45,811 individuals who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) 2008 to 2012. Among these, 2593 (5.7%) participants were identified as having type 2 diabetes mellit...

Diabetes mellitus (DM) and thyroid dysfunction are the two most common endocrinopathies seen in general population. Type 2 diabetes mellitus is commonly associated with altered thyroid function. Aim of the present study is to reveal the prevalence of thyroid dysfunction in patients of Type 2 diabetes mellitus. In the present study 50 type 2 diabetic subjects and 50 healthy non diabetic subjects...

Diabetes mellitus is a metabolic disorder which is characterized by multiple long-term complications that affect almost every system in the body. Foot ulcers are one of the main complications of diabetes mellitus. However, there is limited evidence on the occurrence of foot ulcer and influencing factors in Ethiopia. An institutional-based cross-sectional study was conducted in Gondar University...

Aim: The aim of this study was to analyze cytologically the buccal mucosa, tonge dorsum and floor of the mouth in diabetic patients and healthy volunteers to determine what cellular changes are affected by diabetes mellitus. Method: In order to evaluate cellular changes induced by diabetes mellitus, exfoliative cytology was used for the analysis of buccal mucosa, tongue dorsum and floor of the ...

BACKGROUND/AIMS Abnormal visceral sensitivity and disordered motility are common in patients with diabetes mellitus. The purpose of the present study was to investigate whether visceral sensation and bowel motility were altered in a rat model of type 2 diabetes mellitus accompanied by weight loss. METHODS A type 2 diabetic rat model in adulthood was developed by administrating streptozotocin ...

BACKGROUND/AIM To compare the central corneal thickness (CCT) of type II diabetes mellitus patients with age- and sex-matched healthy subjects and to determine the association of the severity of diabetic retinopathy and CCT. MATERIALS AND METHODS Type II diabetes mellitus patients without retinopathy, with nonproliferative retinopathy, and with proliferative retinopathy were organized as the ...